alpha-1 acid glycoprotein; orosomucoid
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Introduction
Product of a multigene family.
Pathology
- elevated in chronic inflammatory & degenerative disease
- highly elevated in a number of different malignant diseases
Pharmacology
- the major protein in plasma which binds basic drugs
Laboratory
- serum protein electrophoresis
- orosomucoid or alpha-1 acid glycoprotein normally accounts for <30% of alpha-1 band
- generally responsible for elevation of the alpha-1 fraction
- labs with Loincs
More general terms
More specific terms
- alpha-1-acid glycoprotein 1; AGP 1; orosomucoid-1; OMD 1 (ORM1, AGP1)
- alpha-1-acid glycoprotein 2; AGP 2; orosomucoid-2; OMD 2 (ORM2, AGP2)
References
- ↑ Tietz Fundamentals of Clinical Chemistry 3rd ed, WB Saunders, 1987 pg 330
- ↑ OMIM https://mirror.omim.org/entry/176300
- ↑ Clinical Diagnosis & Management by Laboratory Methods, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1991, pg 224
- ↑ Clinical Chemistry, Principles, Procedures, Correlations, 2nd ed., Bishop, Duben-Engelkirk, Fody (eds), JB Lippincott, Philadelphia, 1991 pg 183