cisplatin (Platinol)

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Indications

Powder for injection: 10 mg, 50 mg

Aqueous vials: 50 mg, 100 mg

Needles, syringes, catheters etc for administration of cisplatin should NOT contain aluminum

Monitor

creatinine, CBC, hearing, neurologic function

Adverse effects

Poisoning: antidote is sodium thiosulfate

Drug interactions

Mechanism of action

More general terms

Additional terms

References

  1. Jump up to: 1.0 1.1 Kaiser Permanente Northern California Regional Drug Formulary, 1998
  2. Jump up to: 2.0 2.1 Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 598
  4. Jump up to: 4.0 4.1 4.2 Medical Knowledge Self Assessment Program (MKSAP) 11, 16, 17. American College of Physicians, Philadelphia 1998, 2012, 2015
  5. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 529
  6. Jump up to: 6.0 6.1 6.2 Deprecated Reference
  7. Jump up to: 7.0 7.1 Daenen LGM et al Increased Plasma Levels of Chemoresistance-Inducing Fatty Acid 16:4(n-3) After Consumption of Fish and Fish Oil. JAMA Oncol. Published online April 02, 2015. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26181186 <Internet> http://oncology.jamanetwork.com/article.aspx?articleid=2212208
  8. Jump up to: 8.0 8.1 Brock PR, Maibach R, Childs M et al Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss. N Engl J Med 2018; 378:2376-2385. June 21, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29924955 https://www.nejm.org/doi/full/10.1056/NEJMoa1801109
  9. Jump up to: 9.0 9.1 NEJM Knowledge+
    Gilreath JA, Rodgers GM. How I treat cancer-associated anemia. Blood. 2020 Aug 13;136(7):801-813. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32556170 Free article. Review.

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