creatinine

Pathology

• in congestive heart failure & in uncontrolled diabetes, tubular reabsorption of creatinine may occur

Physiology

• creatinine is formed through non-enzymatic dehydration of tissue creatine
• muscle contains 98% of total body creatine
• creatinine is not recycled, or used in metabolism, thus represents a waste product of creatine metabolism

• creatinine is filtered by glomeruli, but is not reabsorbed to an appreciable extent under normal conditions
• creatinine is also excreted by the proximal tubules in normal individuals adding & an additional 10-40% to the total creatinine in urine

Laboratory

• creatinine in gastric fluid
• creatinine in vitreous fluid
• creatinine in synovial fluid
• creatinine in dialysis fluid
  • creatinine in peritoneal dialysis fluid
• creatinine in CSF
• creatinine in blood
• creatinine in serum/plasma
  • creatinine/BUN ratio
• creatinine in stool
• creatinine in urine
  • urine creatinine ratio
• creatinine clearance

More general terms

• imidazole; glyoxaline; 1,3-diazole; iminazole

Additional terms

• creatine
• creatinine in 24 hour urine
• creatinine in body fluid

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=588