retinoblastoma-associated protein (pRb, Rb, pp110, p105-Rb, p110Rb, RB1)

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Function

Structure

belongs to the retinoblastoma protein (RB) family

Compartment

nucleus

Expression

expressed in the retina

Pathology

Laboratory

Comparative biology

More general terms

Additional terms

References

  1. Seizinger & Breakefield TINS 13(1) 3 (1990)
  2. Wilcock D, Lane DP. Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells. Nature. 1991 Jan 31;349(6308):429-31. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1671528
  3. Hunter T. Cooperation between oncogenes. Cell. 1991 Jan 25;64(2):249-70. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1988147
  4. Dynlacht BD. Retinoblastoma protein. Pol I gets repressed. Nature. 1995 Mar 9;374(6518):114. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7877677
    Cavanaugh AH, Hempel WM, Taylor LJ, Rogalsky V, Todorov G, Rothblum LI. Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product. Nature. 1995 Mar 9;374(6518):177-80. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7877691
  5. 5.0 5.1 Cordon-Cardo C. Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia. Am J Pathol. 1995 Sep;147(3):545-60. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7677168
  6. 6.0 6.1 White RJ, Trouche D, Martin K, Jackson SP, Kouzarides T. Repression of RNA polymerase III transcription by the retinoblastoma protein. Nature. 1996 Jul 4;382(6586):88-90. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8657311
  7. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5925
  8. RB1base; Note: RB1 mutation db http://rb1-lsdb.d-lohmann.de/
  9. Atlas of genetics & cytogenetics in oncology & haematology http://atlasgeneticsoncology.org/genes/RB1ID90.html
  10. GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=RB1
  11. Wikipedia; Note: retinoblastoma protein entry http://en.wikipedia.org/wiki/retinoblastoma_protein
  12. UniProt http://www.uniprot.org/uniprot/P06400.html

Database