AT-rich interactive domain-containing protein 3B (ARID domain-containing protein 3B, bright-like, bright & dead ringer protein, ARID3B, BDP, DRIL2)

Function

• transcription factor
• favors nuclear targeting of ARID3A
• heterodimer with ARID3A
• interacts with unphosphorylated RB1

Structure

contains 1 ARID domain

Compartment

nucleus

Alternative splicing

named isoforms=3

Expression

• expressed in placenta, testis & leukocytes

Pathology

• expressed in neuroblastoma
• role in neuroblastoma growth & malignant transformation (putative)
• present in K562 erythrocytic leukemia cells (at protein level)

More general terms

• AT-rich interactive domain-containing protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IVW6.html