c-myc proto-oncogene protein; transcription factor p64 (c-Myc, MYC)

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Function

Structure

Compartment

nucleus

Expression

Pathology

More general terms

Additional terms

References

  1. Dwarki VJ, Montminy M, Verma IM. Both the basic region and the 'leucine zipper' domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation. EMBO J. 1990 Jan;9(1):225-32. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2136830
  2. Rogers S et al, Amino acids common to rapidly degraded proteins: The PEST hypothesis Science 234:364 1986 (1/2life) PMID: https://www.ncbi.nlm.nih.gov/pubmed/2876518
  3. Blackwell TK, Kretzner L, Blackwood EM, Eisenman RN, Weintraub H. Sequence-specific DNA binding by the c-Myc protein. Science. 1990 Nov 23;250(4984):1149-51. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2251503
  4. Pelengaris S, Khan M, Evan G. c-MYC: more than just a matter of life and death. Nat Rev Cancer. 2002 Oct;2(10):764-76. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12360279
  5. 5.0 5.1 Seoane J et al Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature. 2002 Oct 17;419(6908):729-34. Epub 2002 Oct 2. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12384701
  6. Herschman HR Extracellular signals, transcriptional responses and cellular specificity TIBS 14:455 1989 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2696174
  7. Atlas of genetics & cytogenetics in oncology & haematology http://atlasgeneticsoncology.org/genes/MYCID27.html Wikipedia; Note: Myc entry http://en.wikipedia.org/wiki/Myc
  8. UniProt http://www.uniprot.org/uniprot/P01106.html

Database