c-myc proto-oncogene

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Introduction

oncogene, avian myelocytomatosis virus; There exists an inverse relationship with c-myc expression & cellular differentiation.

More general terms

References

  1. Herschman HR Extracellular signals, transcriptional responses and cellular specificity TIBS 14:455 1989 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2696174
  2. Mudryj M, Hiebert SW, Nevins JR. A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway. EMBO J. 1990 Jul;9(7):2179-84. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2141565
  3. OMIM https://mirror.omim.org/entry/190080
  4. Postel EH, Berberich SJ, Flint SJ, Ferrone CA. Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis. Science. 1993 Jul 23;261(5120):478-80. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8392752

Database