protein BTG1; B-cell translocation gene 1 protein (BTG1)

Function

anti-proliferative protein

Structure

belongs to the BTG family

Expression

• expression is associated with the early G1 phase of the cell cycle

Pathology

• chromosomal translocation t(8;12)(q24;q22) involving BTG1 with MYC may be a cause of a form of B-cell chronic lymphocytic leukemia

More general terms

• anti-oncoprotein (tumor suppressor protein)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=694
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:694
• OMIM: https://mirror.omim.org/entry/109580
• UniProt: http://www.uniprot.org/uniprot/P62324.html