relapsing polychondritis

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Introduction

Episodic & often progressive inflammatory disorder affecting the cartilage of the ear, nose & tracheobronchial tree.

Etiology

Epidemiology

  • most common between age 40-60, but may affect children or elderly
  • relatively uncommon
  • all races

Pathology

Clinical manifestations

* (presenting/cumlative frequencies)

# images[9]

Diagnostic criteria

Laboratory

Diagnostic procedures

Radiology

Complications

Management

More general terms

Additional terms

References

  1. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 1951-53
  2. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 173, 789
  3. 3.0 3.1 3.2 3.3 Medical Knowledge Self Assessment Program (MKSAP) 11, 14, 15, 16, 17, 18, 19. American College of Physicians, Philadelphia 1998, 2006, 2009, 2012, 2015, 2018, 2022.
  4. Leroux G et al Treatment of relapsing polychondritis with rituximab: A retrospective study of nine patients. Arthritis Rheum 2009 May 15; 61:577 PMID: https://www.ncbi.nlm.nih.gov/pubmed/19405005
  5. Rafeq S, Trentham D, Ernst A. Pulmonary manifestations of relapsing polychondritis. Clin Chest Med. 2010 Sep;31(3):513-8 PMID: https://www.ncbi.nlm.nih.gov/pubmed/20692543
  6. Kent PD, Michet CJ Jr, Luthra HS. Relapsing polychondritis. Curr Opin Rheumatol. 2004 Jan;16(1):56-61. PMID: https://www.ncbi.nlm.nih.gov/pubmed/14673390
  7. Chopra R, Chaudhary N, Kay J. Relapsing polychondritis. Rheum Dis Clin North Am. 2013 May;39(2):263-76. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23597963
  8. McAdam LP, O'Hanlan MA, Bluestone R, Pearson CM. Relapsing polychondritis: prospective study of 23 patients and a review of the literature. Medicine (Baltimore). 1976 May;55(3):193-215. PMID: https://www.ncbi.nlm.nih.gov/pubmed/775252
  9. 9.0 9.1 Haslag-Minoff J, Regunath H. Relapsing Polychondritis. Images in Clinical Medicine. N Engl J Med 2018; 378:1715. May 3, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29719184 https://www.nejm.org/doi/full/10.1056/NEJMicm1713302
  10. Vitale A, Sota J, Rigante D et al Relapsing Polychondritis: an Update on Pathogenesis, Clinical Features, Diagnostic Tools, and Therapeutic Perspectives. Curr Rheumatol Rep. 2016 Jan;18(1):3. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/26711694
  11. 11.0 11.1 NEJM Knowledge+
    Kingdon J, Roscamp J, Sangle S, D'Cruz D. Relapsing polychondritis: a clinical review for rheumatologists. Rheumatology (Oxford). 2018 Sep 1;57(9):1525-1532. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29126262 Review.
    Longo L, Greco A, Rea A, Lo Vasco VR, De Virgilio A, De Vincentiis M. Relapsing polychondritis: A clinical update. Autoimmun Rev. 2016 Jun;15(6):539-43. PMID: https://www.ncbi.nlm.nih.gov/pubmed/26876384 Review.

Patient information

relapsing polychondritis patient information