proteoglycan

Introduction

Complex glycoconjugates containing a core protein with a variable number of covalently attached glycosaminoglycan chains (i.e. heparin sulfate, chondroitin sulfate). The glycosaminoglycans are attached to the core proteins through a xyloside linked to Ser of the core protein.

Cell surface receptors often associate with cell-surface proteoglycan, which serves to non-specifically bind proteins & present them for specific binding to the receptor.

More general terms

• glycoconjugate
• polysaccharide (complex carbohydrate, glycan)
• protein
• macromolecular complex

More specific terms

• chondroitin sulfate proteoglycan
• dermatan sulfate proteoglycan
• heparan proteoglycan
• heparan sulfate proteoglycan
• interphotoreceptor matrix proteoglycan 2 (sialoprotein associated with cones & rods proteoglycan, Spacrcan, interphotoreceptor matrix proteoglycan of 200 kD, IPM 200) (IMPG2 IPM200)
• keratan sulfate proteoglycan