leukocytosis
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Introduction
An increase in white blood cells (leukocytes) in peripheral blood. Generally, an increase in neutrophils (neutrophilia), but may be an increase in lymphocytes (lymphocytosis) especially in lymphoproliferative disorders.
Classification
Etiology
- increased production
- idiopathic
- drug-induced -> corticosteroids
- infection
- inflammation
- myeloproliferative disorders
- increased mobilization from the bone marrow
- corticosteroids
- acute infection (endotoxin)
- inflammation (thermal injury)
- defective margination
- pharmaceutical agents
- stress
- excitement
- vigorous exercise
- leukocyte adhesion protein (C3bi {CR3} receptor) deficiency
- miscellaneous
- metabolic disorders
- drugs -> lithium
- metastatic carcinoma
- acute hemorrhage
- hemolysis
- also see lymphocytosis