rheumatoid factor (RF)
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Etiology
- disorders most likely to have high titers
- rheumatoid arthritis (80%, 50% in elderly)
- often negative in early phases of RA
- Sjogren's syndrome
- mixed cryoglobulinemia
- subacute bacterial endocarditis
- rheumatoid arthritis (80%, 50% in elderly)
- disorders with low titers
- systemic lupus erythematosus
- scleroderma (systemic sclerosis)
- mixed connective tissue disease
- sarcoidosis
- idiopathic pulmonary fibrosis
- hypergammaglobulinemic purpura
- asbestosis
- malignancies
- infectious mononucleosis
- influenza
- chronic active hepatitis (B & C)
- vaccinations
- tuberculosis
- syphilis
- Brucellosis
- Leprosy
- Salmonellosis
- Malaria
- Kala-azar
- Schistosomiasis
- Filariasis
- Trypanosomiasis
- rubella
More general terms
Additional terms
Component of
References
- ↑ Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 471, 475, 1019
- ↑ Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 826
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11, 17. American College of Physicians, Philadelphia 1998, 2015
- ↑ Nielsen SF et al. Elevated rheumatoid factor and long term risk of rheumatoid arthritis: A prospective cohort study. BMJ 2012 Sep 6; 345:e5244 PMID: https://www.ncbi.nlm.nih.gov/pubmed/22956589
Simard JF and Holmqvist M. Rheumatoid factor positivity in the general population. BMJ 2012 Sep 6; 345:e5841 PMID: https://www.ncbi.nlm.nih.gov/pubmed/22956591