plasma cell

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[1][2]

Introduction

CD38+, syndecan-1+, CD19+, CD56- or (weak)

Plasma cells are derived from lymph node germinal center B-cells via differentiation into memory B-cells & plasma cells through interaction with T-cells & follicular dendritic cells.

Plasma cells die via apoptosis after several weeks to months. Each plasma cell may produce 1 ng of immunoglobulin/day.

More general terms

Additional terms

References

  1. ↑ Bataille R, Harousseau JL. Multiple myeloma. N Engl J Med. 1997 Jun 5;336(23):1657-64. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/9171069
  2. ↑ Kelly DF et al, Immunological memory: The role of B cells in long-term production against invasive bacterial pathogens. JAMA 2005; 294:3019
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