flow-volume loop
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Indications
Clinical significance
Characteristic patterns occur for certain respiratory disorders:
- a plateau during forced inspiration is characteristic of extrathoracic upper airway obstruction (paradoxical vocal cord motion)
- a plateau during forced expiration is characteristic of intrathoracic upper airway obstruction (tumor compressing trachea)
- MKSAP20 offers variable intrathoracic airway obstruction[1]
- a plateau during both forced inspiration & expiration is characteristic of a fixed upper airway obstruction such as tracheal stenosis*
- low flow rates with minimal change with bronchodilation occur with chronic obstructive lung disease
- low flow rates that improve with bronchodilation characterize reactive airway disease, i.e. asthma
* beware of inspiratory loop being rounded, but insufficiently dome shaped
Procedure
- graphic displays of lung volume & airflow.
- inspiration is represented in the flow-volume loop below the x axis[2]
* ref[2] shows classic flow-volume loop.
* refs[3][4] show other (less useful) flow-volume loops.
Radiology
- Chest CT to confirm an intrathoracic airway obstruction
- allows visualization of intrathoracic airways[1]
- any patient with a focal wheeze should undergo chest CT to rule out an endobronchial lesion[1]
Management
- MKSAP20 does not address management of inspiratory vs expiratory wheezes, or management of fixed obstruction since only the expiratory phase of the flow-volume loop is shown[1] flow-volume loop
More general terms
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Medical Knowledge Self Assessment Program (MKSAP) 11, 14, American College of Physicians, Philadelphia 1998. 2006
Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025 - ↑ 2.0 2.1 2.2 Lung Function Tests. Flow-Volume Loops. MedSchool. Feb 15, 2021 https://medschool.co/tests/lung-function/flow-volume-loops
- ↑ 3.0 3.1 Vitalograph. May 21, 2025 Spirometry - Understanding the Flow Volume Loop. https://vitalograph.com/vital-insights/respiratory-insights/spirometry-understanding-the-flow-volume-loop
- ↑ 4.0 4.1 Karkhanis VS, Desai U, Joshi JM Flow volume loop as a diagnostic marker Lung India. 2013 Apr-Jun;30(2):166-168 PMID: https://pubmed.ncbi.nlm.nih.gov/23741103 PMCID: PMC3669562 Free PMC article