thiazide diuretic

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[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]

Indications

* calcium channel blocker is alternative except in patients with heart failure[2]

* chlorthalidone no better than hydrochlorothiazide[16]

Contraindications

Pharmacokinetics

Adverse effects

Drug interactions

Mechanism of action

More general terms

More specific terms

Component of

References

  1. ↑ Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 137
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Medical Knowledge Self Assessment Program (MKSAP) 11, 16, 17. American College of Physicians, Philadelphia 1998, 2012, 2015
    Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025
  3. ↑ Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  4. ↑ Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 473
  5. ↑ 5.0 5.1 Taylor EN et al, Antihypertensive medications and the risk of incident type 2 diabetes. Diabetes Care 2006; 29:1065 PMID: https://pubmed.ncbi.nlm.nih.gov/16644638
  6. ↑ Prescriber's Letter 14(1): 2007 Thiazides and Diabetes Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=230103&pb=PRL (subscription needed) http://www.prescribersletter.com
  7. ↑ Prescriber's Letter 18(3): 2011 Prescriber's Letter 19(2): 2012 COMMENTARY: Thiazides for Hypertension CHART: Comparison of Commonly Used Diuretics Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=270304&pb=PRL Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=280223&pb=PRL (subscription needed) http://www.prescribersletter.com
  8. ↑ 8.0 8.1 Weber MA et al. Effects of body size and hypertension treatments on cardiovascular event rates: Subanalysis of the ACCOMPLISH randomised controlled trial. Lancet 2013 Feb 16; 381:537 PMID: https://pubmed.ncbi.nlm.nih.gov/23219284
    Messerli FH and Bangalore S. Diuretic-based regimens for obese patients? Lancet 2013 Feb 16; 381:512. PMID: https://pubmed.ncbi.nlm.nih.gov/23219285
  9. ↑ Palmer BF, Naderi AS. Metabolic complications associated with use of thiazide diuretics. J Am Soc Hypertens. 2007 Nov-Dec;1(6):381-92 PMID: https://pubmed.ncbi.nlm.nih.gov/20409871
  10. ↑ 10.0 10.1 Liamis G, Rodenburg EM, Hofman A, et al. Electrolyte disorders in community subjects: prevalence and risk factors. Am J Med. 2013;126:256-263 PMID: https://pubmed.ncbi.nlm.nih.gov/23332973
  11. ↑ 11.0 11.1 11.2 Griebeler ML, Kearns AE, Ryu E, et al. Thiazide-associated hypercalcemia: Incidence and association with primary hyperparathyroidism over two decades. J Clin Endocrinol Metab 2016 Mar; 101:1166-1173. <PubMed> PMID: https://pubmed.ncbi.nlm.nih.gov/26751196 PMCID: PMC480317 Free PMC article <Internet> http://press.endocrine.org/doi/10.1210/jc.2015-3964
  12. ↑ 12.0 12.1 Hall JJ et al. Thiazide diuretic-induced change in fasting plasma glucose: A meta-analysis of randomized clinical trials. J Gen Intern Med 2020 Jun; 35:1849. PMID: https://pubmed.ncbi.nlm.nih.gov/32157653 Review. https://link.springer.com/article/10.1007/s11606-020-05731-3
  13. ↑ 13.0 13.1 Schneider R, Reinau D, Stoffel S et al Risk of skin cancer in new users of thiazides and thiazide-like diuretics: a cohort study using an active comparator group. Br J Dermatol. Published online February 20, 2021 PMID: https://pubmed.ncbi.nlm.nih.gov/33609289
  14. ↑ 14.0 14.1 Carroll L Common Blood Pressure Medications Linked to Increased Skin Cancer Risk. Medscape cites Reuters Health Information April 13, 2021 https://www.medscape.com/viewarticle/949153
    Drucker AM, Hollestein L, Na Y et al Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study. CMAJ. 2021 Apr 12;193(15):E508-E516. Apr 12 PMID: https://pubmed.ncbi.nlm.nih.gov/33846199 Free article. https://www.cmaj.ca/content/193/15/E508
  15. ↑ 15.0 15.1 Ravioli S et al. Risk of electrolyte disorders, syncope, and falls in patients taking thiazide diuretics: Results of a cross-sectional study. Am J Med 2021 Sep; 134:1148. PMID: https://pubmed.ncbi.nlm.nih.gov/33974908 https://www.amjmed.com/article/S0002-9343(21)00289-8/fulltext
  16. ↑ 16.0 16.1 Ishani A, Cushman WC, Leatherman SM et al Chlorthalidone vs. Hydrochlorothiazide for Hypertension - Cardiovascular Events. N Engl J Med 2022. Dec 14 PMID: https://pubmed.ncbi.nlm.nih.gov/26760416 https://www.nejm.org/doi/10.1056/NEJMoa2212270
  17. ↑ 17.0 17.1 Andersson NW, Wohlfahrt J, Feenstra B, Hviid A, Melbye M, Lund M. Cumulative Incidence of Thiazide-Induced Hyponatremia. A Population-Based Cohort Study. Ann Inter Med 2023. Dec 19. PMID: https://pubmed.ncbi.nlm.nih.gov/38109740 https://www.acpjournals.org/doi/full/10.7326/M23-1989
  18. ↑ 18.0 18.1 18.2 NEJM Knowledge+
  19. ↑ 19.0 19.1 Achinger SG, Ayus JC, Kumar A, Tsalatsanis A. Thiazide-Associated Hyponatremia and Mortality Risk: A Cohort Study. Kidney Med. 2024 Dec 9;7(2):100941. PMID: https://pubmed.ncbi.nlm.nih.gov/39866296 Free PMC article. PMCID: https://pmc.ncbi.nlm.nih.gov/articles/PMC11759562/ https://www.kidneymedicinejournal.org/article/S2590-0595(24)00152-3/fulltext
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