drug interaction(s) SGLT2 inhibitors (flozins) with diuretics
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Drug interactions
- SGLT2 inhibitors (flozins) increase the hypotensive & hypovolemic effects of diuretics[1]
- discontinue diuretic if signs of hypotension & hypovolemia[3]
More general terms
References
- ↑ 1.0 1.1 Baker WL, Smyth LR, Riche DM, Bourret EM, Chamberlin KW, White WB. Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis. J Am Soc Hypertens. 2014 Apr;8(4):262-75.e9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24602971 Review.
- ↑ Dubrofsky L, Srivastava A, Cherney DZ Sodium-Glucose Cotransporter-2 Inhibitors in Nephrology Practice: A Narrative Review. Can J Kidney Health Dis. 2020 Jun 24;7:2054358120935701. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32637144 PMCID: PMC7315675 Free PMC article. Review.
- ↑ 3.0 3.1 NEJM Knowledge+ Endocrinology