impaired glucose tolerance
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Etiology
- artificial sweeteners can alter the gut microbiome leading to absorption of more calories & glucose intolerance[5]
Epidemiology
Laboratory
- fasting plasma glucose 110-126 mg/dL.
- two hour glucose on glucose tolerance testing 140-200 mg/dL
* case presentation[6] with fasting plasma glucose of 94 mg/dL, HgbA1c of 6.1% & two hour glucose on glucose tolerance testing 177 mg/dL (no additional testing needed)
Management
More general terms
Additional terms
- diabetes mellitus type 2 (insulin-resistant)
- glucose (dextrose, D-glucose)
- glucose challenge (tolerance) test
- insulin resistance
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
- ↑ Jump up to: 2.0 2.1 2.2 Journal Watch 22(8):61, 2002 Sinba R et al N Engl J Med 346:802, 2002 Rocchini AP N Engl J Med 346:854, 2002
- ↑ Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004
- ↑ Jump up to: 4.0 4.1 4.2 Prescriber's Letter 10(9):49 2003
- ↑ Jump up to: 5.0 5.1 Suez J et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature 2014 Oct 9; 514:181 PMID: https://www.ncbi.nlm.nih.gov/pubmed/25231862
- ↑ Jump up to: 6.0 6.1 NEJM Knowledge+ Question of the Week. July 30, 2019 https://knowledgeplus.nejm.org/question-of-week/868/