polythiazide (Renese)

Indications

• adjunctive therapy in edema associated with
  • congestive heart failure
  • hepatic cirrhosis
  • other causes of edema
• treatment of hypertension

Dosage

• 1-4 mg PO QD

Adverse effects

• GI
  • anorexia
  • gastric irritation
  • nausea/vomiting
  • cramping
  • diarrhea
  • constipation
  • jaundice (intrahepatic cholestatic jaundice)
  • pancreatitis
• CNS
  • dizziness, vertigo
  • paresthesias
  • headache
  • xanthopsia
• hematology
  • leukopenia
  • agranulocytosis
  • thrombocytopenia
  • aplastic anemia
• dermatology/hypersensitivity reactions
  • purpura
  • photosensitivity
  • rash
  • urticaria
  • necrotizing angiitis (vasculitis) (cutaneous vasculitis)
• cardiovascular
  • orthostatic hypotension
• other
  • hyperglycemia
  • glycosuria
  • hyperuricemia
  • muscle spasm
  • weakness

• drug adverse effects of renin-angiotensin-aldosterone system inhibitors (RAAS inhibitors)
• drug adverse effects of thiazide diuretics
• drug adverse effects of diuretics
• drug adverse effects of antihypertensive agents

More general terms

• thiazide diuretic

Component of

• Minizide (prazosin/polythiazide)
• polythiazide/reserpine
• polythiazide/prazosin