drug adverse effects of thiazide diuretics

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Adverse effects

* thiazides & beta-blockers may cause glucose intolerance

* older patients are especially vulnerable to the adverse effects of thiazide diuretics, including renal-electrolyte disturbances, gout, hyperglycemia, & hypotension[4]

* do not change loop diuretic to thiazide diuretic for hyperkalemia in patients with systolic heart failure[5]

More general terms

References

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  7. 7.0 7.1 Schneider R, Reinau D, Stoffel S et al Risk of skin cancer in new users of thiazides and thiazide-like diuretics: a cohort study using an active comparator group. Br J Dermatol. Published online February 20, 2021 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33609289
  8. 8.0 8.1 Carroll L Common Blood Pressure Medications Linked to Increased Skin Cancer Risk. Medscape cites Reuters Health Information April 13, 2021 https://www.medscape.com/viewarticle/949153
    Drucker AM, Hollestein L, Na Y et al Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study. CMAJ. 2021 Apr 12;193(15):E508-E516. Apr 12 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33846199 Free article. https://www.cmaj.ca/content/193/15/E508
  9. 9.0 9.1 Ravioli S et al. Risk of electrolyte disorders, syncope, and falls in patients taking thiazide diuretics: Results of a cross-sectional study. Am J Med 2021 Sep; 134:1148. PMID: https://www.ncbi.nlm.nih.gov/pubmed/33974908 https://www.amjmed.com/article/S0002-9343(21)00289-8/fulltext
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  11. NEJM Knowledge+