bendroflumethiazide; bendrofluazide (Naturetin)

From Aaushi
Jump to navigation Jump to search

Introduction

Thiazide diuretic used in ASCOT BPLA trial.

Dosage

  • start 5 mg PO QD
  • max 20 mg/day
  • maintenance 2.5-5 mg QD
  • 1.25-2.5 mg PO QD elderly

* Tabs: 5 & 10 mg

Adverse effects

Drug interactions

More general terms

Component of

References

  1. Dahlf B et al. for the ASCOT Investigators. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16154016 Lancet 2005 Sep 10; 366:895-906.
    Staessen JA and Birkenhager WH. Evidence that new antihypertensives are superior to older drugs. Lancet 2005 Sep 10; 366:869-71. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16153995
  2. Drugs.com: Naturetin https://www.drugs.com/pro/naturetin.html

Database