sulindac (Clinoril)

From Aaushi
Jump to navigation Jump to search

Introduction

Tradename Clinoril.

Indications

Dosage

150-200 mg PO BID with food; max 400 mg/day

Tabs: 150, 200 mg.

Pharmacokinetics

elimination via liver

1/2life = 7 hours

1/2life = 16 hours active sulfide

protein binding = 93 %

elimination by hemodialysis = -

elimination by peritoneal dialysis = -

Monitor

Adverse effects

Drug interactions

Laboratory

Mechanism of action

More general terms

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 792
  3. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  4. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  5. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  6. 6.0 6.1 Prescriber's Letter 10(5):29 2003
  7. 7.0 7.1 Prescriber's Letter 17(7): 2010 Recommended Lab Monitoring for Common Medications Liver Function Test Scheduling Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=260704&pb=PRL (subscription needed) http://www.prescribersletter.com

Database