piroxicam (Feldene)

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Introduction

Tradename: Feldene.

Indications

Dosage

  • 20 mg PO QD
  • do not assess effect of therapy for 2 weeks
  • use with caution or reduced doses in the elderly

Tabs: 10, 20 mg.

Pharmacokinetics

elimination via liver

1/2life = 14-158 hours

protein binding = >99 %

elimination by hemodialysis = -

elimination by peritoneal dialysis = -

Monitor

liver function tests periodically[6]

Adverse effects

Drug interactions

Laboratory

Mechanism of action

More general terms

Additional terms

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  5. 5.0 5.1 Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 470
  6. 6.0 6.1 Prescriber's Letter 17(7): 2010 Recommended Lab Monitoring for Common Medications Liver Function Test Scheduling Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=260704&pb=PRL (subscription needed) http://www.prescribersletter.com

Database