Wnt/beta-catenin induced genes

Introduction

genes induced by canonical wnt pathway/beta-catenin include:

• c-myc
• cyclin D
• tcf-1
• lef1
• PPar-delta
• c-jun
• fra-1
• uPAR
• matrix metalloproteinase 7 (MMP-7)
• matrix metalloproteinase 26 (MMP-26)
• axin-2
• Nr-CAM
• ITF-2
• gastrin
• CD44
• ephrin-B
• BMP4
• claudin-1
• survivin
• VEGF
• FGF4
• FGF18
• FoxN1
• Id2
• twist
• stromelysin
• WISP-1,2
• brachyury
• proglucagon
• cyclooxygenase-2
• neurogenin 1
• proliferin-2,3
• IGF-I,II
• MDR1
• interleukin 6
• betaTrCP
• pitx2
• ret
• connexin43

genes with reduced expression:

• osteocalcin
• periostin
• E-cadherin

More general terms

• unclassified gene

Additional terms

• beta catenin
• wnt proto-oncogene protein or int proto-oncogene protein