P-glycoprotein 1 (PGY1, multidrug resistance protein 1, MDR1, gp170, ATP-binding cassette subfamily B member 1, ABCB1)

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Function

Structure

Compartment

membrane

Expression

Pathology

Polymorphism

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/P08183.html
  2. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5243
  3. 3.0 3.1 Aarnoudse ALHJ et al, MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine. Clin Pharmacol Ther 2006, 80:367 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17015054
  4. Atlas of genetics & cytogenetics in oncology & haematology http://atlasgeneticsoncology.org/genes/PGY1ID105.html
  5. NIEHS-SNPs http://egp.gs.washington.edu/data/abcb1/
  6. SHMPD; The Singapore human mutation and polymorphism database http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=ABCB1
  7. Wikipedia; Note: P-glycoprotein entry http://en.wikipedia.org/wiki/P-glycoprotein

Database