signal transducer & activator of transcription 3; acute-phase response factor (STAT3, APRF)

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Function

Structure

Compartment

Alternative splicing

named isoforms=2

Expression

Pathology

More general terms

Component of

References

  1. Zhang X, Blenis J, Li HC, Schindler C, Chen-Kiang S. Requirement of serine phosphorylation for formation of STAT- promoter complexes. Science. 1995 Mar 31;267(5206):1990-4. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7701321
  2. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6774
  3. 3.0 3.1 Shi X, Zhang H, Paddon H, Lee G, Cao X, Pelech S. Phosphorylation of STAT3 serine-727 by cyclin-dependent kinase 1 is critical for nocodazole-induced mitotic arrest. Biochemistry. 2006 May 9;45(18):5857-67. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16669628
  4. 4.0 4.1 Wang W et al. STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: Dose:response effects of systemic IFN therapy. J Invest Dermatol 2008 Aug; 128:1997. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18305569
  5. Wikipedia; Note: STAT3 entry http://en.wikipedia.org/wiki/STAT3
  6. Atlas of genetics & cytogenetics in oncology & haematology http://atlasgeneticsoncology.org/genes/STAT3ID444.html
  7. Web: Name=SeattleSNPs http://pga.gs.washington.edu/data/stat3/
  8. UniProt http://www.uniprot.org/uniprot/P40763.html

Database