lorazepam (Ativan)

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Introduction

Tradename: Ativan. DEA-controlled substance: class 4.

Indications

Dosage

Tabs: 0.5, 1, 2 mg.

Injection: 2 mg/mL (1 mL, 10 mL), 4 mg/mL (1 mL, 10 mL)

Tabs: 0.5 mg, 1 mg, 2 mg.

Store injectable form in refrigerator.

Pharmacokinetics

elimination via liver

elimination via kidney

1/2life = 8-25 hours

protein binding = 88-92 %

Adverse effects

Drug interactions

Laboratory

Mechanism of action

More general terms

References

  1. 1.0 1.1 The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996.
  2. 2.0 2.1 2.2 2.3 Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 7
  3. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  4. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  5. 5.0 5.1 Clinical Guide to Laboratory Tests, NW Tietz (ed) 3rd ed, WB Saunders, Philadelpha 1995
  6. 6.0 6.1 UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 12-15, 2001
  7. 7.0 7.1 Deprecated Reference
  8. 8.0 8.1 Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022

Database