urinary incontinence (UI)
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Introduction
Involuntary loss of urine sufficient to be a problem. There are several types of UI, but all are characterized by an inability to restrain or control urinary voiding (see mixed urinary incontinence, nocturnal enuresis, overflow incontinence, stress incontinence, transient urinary incontinence, urge incontinence).
Classification
- transient (reversible) urinary incontinence
- stress incontinence
- urge incontinence
- overflow incontinence
- mixed urinary incontinence
- functional (idiopathic) incontinence
Etiology
- reversible factors (DRIP) D: delirium, dementia, depression R: restricted mobility, urinary retention I: infection, inflammation (atrophic vaginitis), fecal impactation P: pharmaceuticals, polyuria (glycosuria, CHF)
- reversible factors (DIAPPERS) D: delirium I: infection A: atrophic vaginitis P: pharmaceuticals P: psychologic factors (depression or behavioral disturbance) E: excess urine output (excess fluid intake, diuretics, edema) R: restricted mobility S: stool impactation
- see more specific type
- see pharmaceutical causes of urinary incontinence
- seizures
Epidemiology
- 15-30% of elderly in the community
- 50-70% of nursing home patients[37]
- strong association with dementia
- 10% of young, nulligravid women[17]
- incidence increases with age
- underdiagnosed & under-reported (63% report to physicans)[8]
- common reason for nursing home placement
History
- malignancies, neuroendocrine disorder, pelvic surgery or irradiation, parity, frequency, dysuria, hematuria, fever, polydipsia, weight gain, change in bowel habits, fecal incontinence, sexual dysfunction, sensory or motor symptoms
- AUA symptom index (men)
Clinical manifestations
- loss of perineal sensation
- loss of bulbocavernosus reflex
- palpable bladder
- urine loss with Valsalva maneuver
- enlarged prostate
- decreased rectal sphincter tone
- impactation
- signs of estrogen deprivation
Laboratory
Diagnostic procedures
- postvoid residual (PVR) in men (prior to discontinuation of medications)[16]
- urodynamic testing
- failure of initial therapy, not reccommended (MKSAP19)[2]
- pad test of standardized duration & activity protocol[33]
Radiology
- pelvic or abdominal ultrasound
- intravenous pyelography (IVP)
- computed tomography (CT) of pelvis
Complications
- urinary tract infections
- skin breakdown: incontinence-associated dermatitis
- falls
- psychologic distress[6]
- depression[21]
- work disability[21]
- disease interaction(s) of venous stasis with urinary incontinence
- disease interaction(s) of obstructive sleep apnea (OSA) with urinary incontinence
- disease interaction(s) of lumbar spinal stenosis with urinary incontinence
- disease interaction(s) of spinal cord injury with urinary incontinence
- disease interaction(s) of Parkinson's disease with urinary incontinence
- disease interaction(s) of normal pressure hydrocephalus (NPH) with urinary incontinence
- disease interaction(s) of multiple sclerosis with urinary incontinence
- disease interaction(s) of dementia with urinary incontinence
- disease interaction(s) of stroke with urinary incontinence
- disease interaction(s) of diabetes mellitus with urinary incontinence
- disease interaction(s) of heart failure with urinary incontinence
Management
- general
- treat reversible causes
- discontinue offending medications
- try the least invasive intervention 1st
- weight reduction & fluid restriction can improve urinary incontinence in selected women[2][9][14]
- voiding diary if etiology is unclear
- limit caffeine intake
- treat constipation
- enhance mobility
- prompted voiding in demented elderly[2]
- bedside commode if mobility impaired
- catheterization
- indications
- avoid chronic catheterization if possible
- treat reversible causes
- see specific type of urinary incontinence
- stable symptoms
- no benefit of treating bacteriuria even with pyuria
- indications for urology referral
- unclear diagnosis after simple bedside tests
- recurrent symptomatic urinary tract infection
- hematuria
- previous lower urinary tract surgical procedures
- trauma
- irradiation
- prostate abnormality with symptomatic obstruction
- marked pelvic prolapse
- inability to pass urethral catheter
- significant urinary retention (> 200 mL PVR*)
- abnormal renal function with symptoms of retention
- lack of response to treatment
- devices
- periurethral bulking injection (see periurthethral ...)
- not effective[36]
- pelvic muscle exercises (stress & urge incontinence)
- screening for urinary incontinence recommended annually at preventive health visits for all women of all ages[34]
- prevention (see prevention of fecal & urinary incontinence)
More general terms
More specific terms
- enuresis
- functional incontinence
- involuntary detrusor contraction
- mixed urinary incontinence
- overflow incontinence
- stress urinary incontinence
- transient (reversible) urinary incontinence
- urge incontinence
Additional terms
- incontinence-associated dermatitis
- office evaluation of urinary incontinence
- pharmaceutical causes of urinary incontinence
- pharmaceuticals used to treat urinary incontinence
- prevention of fecal & urinary incontinence
References
- ↑ Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 528-30
- ↑ 2.0 2.1 2.2 2.3 Medical Knowledge Self Assessment Program (MKSAP) 11, 14, 17, 19. American College of Physicians, Philadelphia 1998, 2006, 2015, 2021
Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022 - ↑ UCLA Specialty Women's clinic, 2001
- ↑ 4.0 4.1 Journal Watch 21(21):168, 2001 Sherburn et al Is incontinence associated with menopause? Obstet Gynecol 98:628, 2001 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11576579
- ↑ Journal Watch 22(18):142, 2002 Buschsbaum GM et al Prevalence of urinary incontinence and associated risk factors in a cohort of nuns. Obstet Gynecol 100:226, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12151141
- ↑ 6.0 6.1 6.2 6.3 Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004; 7th edition 2010
- ↑ Journal Watch 23(20):159, 2003 Grodstein T et al Association of age, race, and obstetric history with urinary symptoms among women in the Nurses' Health Study. Am J Obstet Gynecol 189(Aug):248 2003 PMID: https://www.ncbi.nlm.nih.gov/pubmed/14520212
- ↑ 8.0 8.1 8.2 Journal Watch 24(18):146, 2004 Jackson RA, Vittinghoff E, Kanaya AM, Miles TP, Resnick HE, Kritchevsky SB, Simonsick EM, Brown JS; Health, Aging, and Body Composition Study. Urinary incontinence in elderly women: findings from the Health, Aging, and Body Composition Study. Obstet Gynecol. 2004 Aug;104(2):301-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15292003
- ↑ 9.0 9.1 Journal Watch 25(17):134, 2005 Subak LL, Whitcomb E, Shen H, Saxton J, Vittinghoff E, Brown JS. Weight loss: a novel and effective treatment for urinary incontinence. J Urol. 2005 Jul;174(1):190-5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15947625
Swithinbank L, Hashim H, Abrams P. The effect of fluid intake on urinary symptoms in women. J Urol. 2005 Jul;174(1):187-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15947624 - ↑ Landefeld CS et al, National Institutes of Health state-of-the-science statement: Prevention of fecal and urinary incontinence in adults. Ann Intern Med 2008, 148:449 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18268289 corresponding NGC guideline withdrawn Dec 2013
- ↑ Shamliyan TA et al, Systematic review: Randomized, controlled trials of nonsurgical treatments for urinary incontinence in women. Ann Intern Med 2008, 148:459 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18268288
Huang AJ [Consensus guidelines] Nonsurgical Treatments for Urinary Incontinence in Women: Summary of Primary Findings and Conclusions. JAMA Intern Med. 2013; 173(15):1463-1464 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23817490 - ↑ Minassian VA et al, Urinary incontinence in women: Variation in prevalence estimates and risk factors. Obstet Gynecol 2008, 111:324 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18238969
- ↑ 13.0 13.1 13.2 Waetjen LE, Feng WY, Ye J, Johnson WO, Greendale GA et al; Study of Women's Health Across the Nation (SWAN). Factors associated with worsening and improving urinary incontinence across the menopausal transition. Obstet Gynecol. 2008 Mar;111(3):667-77. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18310370
- ↑ 14.0 14.1 Subak LL et al, Weight Loss to Treat Urinary Incontinence in Overweight and Obese Women N Engl J Med 360:481-490 January 29, 2009 Number 5 http://content.nejm.org/cgi/content/short/360/5/481 PMID: https://www.ncbi.nlm.nih.gov/pubmed/19179316
- ↑ Landefeld CS et al National Institutes of Health state-of-the-science conference statement: prevention of fecal and urinary incontinence in adults. Ann Intern Med. 2008 Mar 18;148(6):449-58. Epub 2008 Feb 11. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18268289
- ↑ 16.0 16.1 Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013 - ↑ 17.0 17.1 O'Halloran T et al Urinary Incontinence in Young Nulligravid Women: A Cross-sectional Analysis Annals of Internal Medicine, July 17 2012 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22801671 <Internet> http://annals.org/article.aspx?articleid=1216553
- ↑ Ruby CM, Hanlon JT, Boudreau RM et al The effect of medication use on urinary incontinence in community-dwelling elderly women. J Am Geriatr Soc. 2010 Sep;58(9):1715-20. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20670377
- ↑ DuBeau CE, Kuchel GA, Johnson T et al Incontinence in the frail elderly: report from the 4th International Consultation on Incontinence. Neurourol Urodyn. 2010;29(1):165-78. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20025027
- ↑ Goode PS, Burgio KL, Richter HE, Markland AD. Incontinence in older women. JAMA. 2010 Jun 2;303(21):2172-81. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20516418
- ↑ 21.0 21.1 21.2 Moore AA NEJM Journal Watch. Women's Health. April 3, 2014 Massachusetts Medical Society http://www.jwatch.org
Hung KJ et al. Urinary incontinence, depression, and economic outcomes in a cohort of women between the ages of 54 and 65 years. Obstet Gynecol 2014 Apr; 123:822 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24785611 <Internet> http://journals.lww.com/greenjournal/pages/articleviewer.aspx?year=2014&issue=04000&article=00015&type=abstract - ↑ National Institute of Aging
Urinary incontinence https://www.nia.nih.gov/health/topics/urinary-incontinence
Urinary Incontinence in Older Adults https://www.nia.nih.gov/health/urinary-incontinence-older-adults - ↑ Evaluation and Management of Urinary Incontinence: recommendations from the Brigham and Women's Hospital, Finnish Medical Society, The John A. Hartford Foundation Institute for Geriatric Nursing, Scottish Intercollegiate Guidelines Network, and the Singapore Ministry of Health. http://www.guideline.gov/Compare/comparison.aspx?file=INCONTINENCE1.inc
- ↑ DuBeau CE. Therapeutic/pharmacologic approaches to urinary incontinence in older adults. Clin Pharmacol Ther. 2009 Jan;85(1):98-102. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19037201
- ↑ Fung CH, Spencer B, Eslami M, Crandall C. Quality indicators for the screening and care of urinary incontinence in vulnerable elders. J Am Geriatr Soc. 2007 Oct;55 Suppl 2:S443-9. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17910569
- ↑ Qaseem A, Dallas P, Forciea MA et al Nonsurgical Management of Urinary Incontinence in Women: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2014;161(6):429-440 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25222388 <Internet> http://annals.org/article.aspx?articleid=1905131
- ↑ Wood LN, Anger JT. Urinary incontinence in women. BMJ. 2014;349:g4531. PMID: https://www.ncbi.nlm.nih.gov/pubmed/25225003
- ↑ Markland AD, Vaughan CP, Johnson TM et al Incontinence. Med Clin North Am. 2011 May;95(3):539-54, x-xi. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21549877
- ↑ Cameron AP, Heidelbaugh JJ, Jimbo M. Diagnosis and office-based treatment of urinary incontinence in adults. Part one: diagnosis and testing. Ther Adv Urol. 2013 Aug;5(4):181-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23904857 Free PMC Article
Cameron AP, Jimbo M, Heidelbaugh JJ. Diagnosis and office-based treatment of urinary incontinence in adults. Part two: treatment. Ther Adv Urol. 2013 Aug;5(4):189-200. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23904858 Free PMC - ↑ DuBeau CE. Therapeutic/pharmacologic approaches to urinary incontinence in older adults. Clin Pharmacol Ther. 2009 Jan;85(1):98-102. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19037201
- ↑ Hersh L, Salzman B. Clinical management of urinary incontinence in women. Am Fam Physician. 2013 May 1;87(9):634-40. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23668526 Free Article
- ↑ Ayeleke RO, Hay-Smith EJ, Omar MI. Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary incontinence in women. Cochrane Database Syst Rev. 2015 Nov 3;(11):CD010551. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/26526663
- ↑ 33.0 33.1 Nambiar AK, Bosch R, Cruz F et al EAU Guidelines on Assessment and Nonsurgical Management of Urinary Incontinence. Eur Urol. 2018 Feb 2. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29398262 <Internet> http://www.europeanurology.com/article/S0302-2838(18)30002-2/fulltext
- ↑ 34.0 34.1 O'Reilly N, Nelson HD, Conry JM et al Screening for Urinary Incontinence in Women: A Recommendation From the Women's Preventive Services Initiative. Ann Intern Med. Aug 14, 2018. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/30105360 <Internet> http://annals.org/aim/fullarticle/2697085/screening-urinary-incontinence-women-recommendation-from-women-s-preventive-services
Nelson HD, Cantor A, Pappas M, Miller L. Screening for Urinary Incontinence in Women: A Systematic Review for the Women's Preventive Services Initiative. Ann Intern Med. Aug 14, 2018. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/30105353 <Internet> http://annals.org/aim/article-abstract/2697084/screening-urinary-incontinence-women-systematic-review-women-s-preventive-services
Bell RJ, Davis SR. Routine Screening for Urinary Incontinence in Women: Caution Advised. Ann Intern Med. Aug 14, 2018. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/30105377 <Internet> http://annals.org/aim/article-abstract/2697086/routine-screening-urinary-incontinence-women-caution-advised - ↑ Judge DE Urinary Incontinence: Yes, It Can Be Treated. NEJM Journal Watch. Jan 22, 2019 Massachusetts Medical Society (subscription needed) http://www.jwatch.org https://www.jwatch.org/na48165/2019/01/22/urinary-incontinence-yes-it-can-be-treated
Fitzgerald JJ, Iglesia CB Treatment Options for Women with Urinary Incontinence. NEJM Journal Watch. Jan 22, 2019 Massachusetts Medical Society (subscription needed) http://www.jwatch.org https://www.jwatch.org/na48035/2019/01/22/treatment-options-women-with-urinary-incontinence - ↑ 36.0 36.1 Balk EM, Rofeberg VN, Adam GP et al Pharmacologic and Nonpharmacologic Treatments for Urinary Incontinence in Women: A Systematic Review and Network Meta-analysis of Clinical Outcomes Ann Intern Med. 2019. March 19. PMID: https://www.ncbi.nlm.nih.gov/pubmed/30884526 https://annals.org/aim/article-abstract/2728712/pharmacologic-nonpharmacologic-treatments-urinary-incontinence-women-systematic-review-network-meta
- ↑ 37.0 37.1 Dumoulin C, Cacciari LP, Hay-Smith EJC. Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women. Cochrane Database Syst Rev. 2018 Oct 4;10(10):CD005654 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30288727 PMCID: PMC6516955 Free PMC article https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005654.pub4/full
- ↑ Talebraza S et al Geriatrics Evaluation & Management Tools American Geriatrics Society. 2021 https://geriatricscareonline.org/ProductAbstract/geriatrics-evaluation-management-tools/B007/
- ↑ National Poll on Healthy Aging Urinary Incontinence: An Inevitable Part of Aging? http://www.healthyagingpoll.org/sites/default/files/2018-11/NPHA_Incontinence-Report_FINAL-110118.pdf