screening for colon cancer

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Epidemiology

Pathology

Indications

Contraindications

  • no benefit for screening[13]
  • men age 75-84 with poor health status
  • men > 85 years of age with average or poor health status
  • women > 90 years of age with average or poor health status
  • elderly > 75 years with limited life expectancy[102]

* up to 50% of veterans feel that limited life expectancy should not influence screening decicions[83]

Benefit/risk

number needed to screen

Laboratory

Diagnostic procedures

Radiology

Notes

out-of-pocket costs

More general terms

Additional terms

References

  1. 1.0 1.1 1.2 Journal Watch 20(24):189, 2000 Ahlquist DA et al Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel. Gastroenterology 119:1219, 2000 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11054379
  2. 2.0 2.1 Mandel JS et al The effect of fecal occult-blood screening on the incidence of colorectal cancer. N Engl J Med 343:1603, 2000 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11096167
  3. 3.0 3.1 Journal Watch 22(5):37-28, 2002 Traverso G et al Detection of APC mutations in fecal DNA from patients with colorectal tumors. N Engl J Med 346:311, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11821507
  4. Wikipedia: Colorectal cancer http://en.wikipedia.org/wiki/Colorectal_Cancer
  5. 5.0 5.1 Journal Watch 23(8):63, 2003 Cui H et al Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 299:1753, 2003 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12637750
    Ranshohoff DF et al Cancer. Developing molecular biomarkers for cancer. Science 299:1679, 2003 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12637728
  6. 6.0 6.1 Journal Watch 20(23):182-183, 2000 Sonnenberg A et al Cost-effectiveness of colonoscopy in screening for colorectal cancer. Ann Intern Med 133:573, 2000 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11033584
    Frazier AL et al Cost-effectiveness of screening for colorectal cancer in the general population. JAMA 284:1954, 2000 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11035892 Inciardi JF et al Incidence trends for colorectal cancer in California: implications for current screening practices. Am J Med 109:277, 2000 PMID: https://www.ncbi.nlm.nih.gov/pubmed/10996577
  7. 7.0 7.1 7.2 Dove-Edwin I, Sasieni P, Adams J, Thomas HJ. Prevention of colorectal cancer by colonoscopic surveillance in individuals with a family history of colorectal cancer: 16 year, prospective, follow-up study. BMJ. 2005 Nov 5;331(7524):1047. Epub 2005 Oct 21. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/16243849 <Internet> http://bmj.bmjjournals.com/cgi/content/full/331/7524/1047
  8. 8.0 8.1 Journal Watch 22(17):137, 2002
    Pignone M et al for the US Preventive Services Task Force Screening for colorectal cancer in adults at average risk: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 137:132, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12118972
    Pignone M et al Cost-effectiveness analyses of colorectal cancer screening: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med 137:96, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12118964
  9. Ko CW & Sonnenberg A Comparing risks and benefits of colorectal cancer screening in elderly patients Gastroenterology 129:1163, 2005 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16230070
  10. 10.00 10.01 10.02 10.03 10.04 10.05 10.06 10.07 10.08 10.09 10.10 Medical Knowledge Self Assessment Program (MKSAP) 11, 14, 16, 17, 18,19. American College of Physicians, Philadelphia 1998, 2006, 2012, 2015, 2018, 2022
  11. 11.0 11.1 Journal Watch 25(4):30, 2005 Collins JF, Lieberman DA, Durbin TE, Weiss DG; Veterans Affairs Cooperative Study #380 Group. Accuracy of screening for fecal occult blood on a single stool sample obtained by digital rectal examination: a comparison with recommended sampling practice. Ann Intern Med. 2005 Jan 18;142(2):81-5. Summary for patients in: Ann Intern Med. 2005 Jan 18;142(2):I23. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15657155
  12. 12.0 12.1 Burke CA et al, Screening for colorectal cancer with flexible sigmoidoscopy: Is a 5-year interval appropriate? A comparison of the detection of neoplasia 3 yr versus 5 yr after normal examination. Am J Gastroenterol 2006; 101:1329 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16771957
  13. 13.0 13.1 Regula J et al, Colonoscopy in colorectal-cancer screening for detection of advanced neoplasia. N Engl J Med 2006, 355:1863 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17079760
  14. 14.0 14.1 14.2 Habermann JK, Roblick UJ, Luke BT, Prieto DA, Finlay WJ, Podust VN, Roman JM, Oevermann E, Schiedeck T, Homann N, Duchrow M, Conrads TP, Veenstra TD, Burt SK, Bruch HP, Auer G, Ried T. Increased serum levels of complement C3a anaphylatoxin indicate the presence of colorectal tumors. Gastroenterology. 2006 Oct;131(4):1020-9; quiz 1284. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17030172
  15. 15.0 15.1 Gross CP et al, Relation between Medicare screening reimbursement and stage at diagnosis for older patients with colon cancer. JAMA 2006, 296:2815 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17179458
  16. 16.0 16.1 16.2 16.3 Itzkowitz SH et al, Improved fecal DNA test for colorectal cancer screening. Clin Gastroentorol Hepatol 2007, 5:111 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17161655
  17. Guittet L et al, Comparison of a guaiac based and an immunochemical faecal occult blood test in screening for colorectal cancer in a general average risk population Gut 2007, 56:210 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16891354
  18. 18.0 18.1 18.2 Levin B et al, Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: A joint guideline from the American Cancer Society, the US Multi-society Task Force on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin 2008 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/18322143 <Internet> http://caonline.amcancersoc.org/cgi/content/full/CA.2007.0018v1 http://dx.doi.org/10.3322/CA.2007.0018
  19. 19.0 19.1 19.2 19.3 19.4 19.5 US Preventive Services Task Force Clinical guidelines Screening for colorectal cancer Ann Intern Med 2008 Oct 6; [e-pub ahead of print]. (corresponding NGC guideline withdrawn Jan 2014) http://www.annals.org/content/149/9/627.full
  20. 20.0 20.1 Van Gossum A et al Capsule Endoscopy versus Colonoscopy for the Detection of Polyps and Cancer N Eng J Med 2009, 361:264-270 July 16, 2009 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/19605831 <Internet> http://content.nejm.org/cgi/content/short/361/3/264
  21. 21.0 21.1 21.2 Atkin WS et al. Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: A multicentre randomised controlled trial. Lancet 2010 May 8; 375:1624. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20430429
    Ransohoff DF. Can endoscopy protect against colorectal cancer? An RCT. Lancet 2010 May 8; 375:1582. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20430430
  22. 22.0 22.1 Henley SJ et al Surveillance of Screening-Detected Cancers (Colon and Rectum, Breast, and Cervix) --- United States, 2004--2006 Surveillance Summaries Morbidity and Mortality Weekly Report (MMWR) November 26, 2010 / 59(SS09);1-25 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/21102407 <Internet> http://www.cdc.gov/mmwr/preview/mmwrhtml/ss5909a1.htm
  23. 23.0 23.1 23.2 Brenner H et al Protection From Colorectal Cancer After Colonoscopy: A Population-Based, Case-Control Study Ann Intern Med January 3, 2011 154:22-30 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21200035
    Weinberg DS Colonoscopy: What Does It Take to Get It 'Right'? Ann Intern Med January 4, 2011 154:68-69 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21200044
  24. 24.0 24.1 Taylor, WC Clinician's Corner, Clinical Crossroads, A 71-year old woman contemplating a screening colonoscopy JAMA 2006; 295:1161
  25. 25.0 25.1 Sequist TD et al. Electronic patient messages to promote colorectal cancer screening: A randomized controlled trial. Arch Intern Med 2011 Apr 11; 171:636 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21149743
  26. 26.0 26.1 26.2 Sonoda H et al. Colorectal cancer screening with odour material by canine scent detection. Gut 2011 Jun; 60:814. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21282130
  27. 27.0 27.1 Segnan N et al. Once-only sigmoidoscopy in colorectal cancer screening: Follow-up findings of the Italian Randomized Controlled Trial
    SCORE. J Natl Cancer Inst 2011 Sep 7; 103:1310 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21852264
  28. Zauber AG et al Colonoscopic Polypectomy and Long-Term Prevention of Colorectal- Cancer Deaths N Engl J Med 2012; 366:687-696February 23, 2012 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22356322 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1100370
    Quintero E et al Colonoscopy versus Fecal Immunochemical Testing in Colorectal- Cancer Screening N Engl J Med 2012; 366:697-706February 23, 2012 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22356323 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1108895
  29. 29.0 29.1 29.2 29.3 29.4 29.5 Qaseem A et al Screening for Colorectal Cancer: A Guidance Statement From the American College of Physicians Annals of Internal Medicine March 6, 2012, 156(5):378-386 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22393133 <Internet> http://www.annals.org/content/156/5/378.full.pdf+html (corresponding NGC guideline withdrawn Nov 2017)
  30. 30.0 30.1 30.2 Ahlquist DA et al. Next-generation stool DNA test accurately detects colorectal cancer and large adenomas. Gastroenterology 2012 Feb; 142:248 PMID: https://www.ncbi.nlm.nih.gov/pubmed/22062357
  31. 31.0 31.1 Inadomi JM et al Adherence to Colorectal Cancer Screening A Randomized Clinical Trial of Competing Strategies Arch Intern Med. 2012;172(7):575-582 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22493463 <Internet> http://archinte.ama-assn.org/cgi/content/short/172/7/575
  32. 32.0 32.1 32.2 Schoen RE et al Colorectal-Cancer Incidence and Mortality with Screening Flexible Sigmoidoscopy N Engl J Med, May 21, 2012 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22612596 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1114635
    Inadomi JM Why You Should Care about Screening Flexible Sigmoidoscopy N Engl J Med, May 21, 2012 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22612597 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMe1204099
  33. 33.0 33.1 Lee SJ et al. Time lag to benefit after screening for breast and colorectal cancer: Meta-analysis of survival data from the United States, Sweden, United Kingdom, and Denmark. BMJ 2013 Jan 8; 346:e8441 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23299842 <Internet> http://www.bmj.com/content/346/bmj.e8441
  34. Doubeni CA et al. Screening colonoscopy and risk for incident late-stage colorectal cancer diagnosis in average-risk adults: A nested case-control study. Ann Intern Med 2013 Mar 5; 158:312 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23460054
  35. 35.0 35.1 Green BB et al. An automated intervention with stepped increases in support to increase uptake of colorectal cancer screening: A randomized trial. Ann Intern Med 2013 Mar 5; 158:301 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23460053
  36. 36.0 36.1 36.2 36.3 Senore C et al. Offering people a choice for colorectal cancer screening. Gut 2013 May; 62:735. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22442162
  37. 37.0 37.1 Hassan C et al Computed tomographic colonography for colorectal cancer screening. Risk factors for the detection of advanced neoplasia. Cancer. June 10, 2013 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23754679 <Internet> http://onlinelibrary.wiley.com/doi/10.1002/cncr.28007/abstract
  38. Nishihara R et al Long-Term Colorectal-Cancer Incidence and Mortality after Lower Endoscopy. N Engl J Med 2013; 369:1095-1105September 19, 2013 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24047059 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1301969
    Shaukat A et al Long-Term Mortality after Screening for Colorectal Cancer. N Engl J Med 2013; 369:1106-1114September 19, 2013 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24047060 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1300720
    Levin TR and Corley DA Colorectal-Cancer Screening - Coming of Age
  39. Ferrante JM et al Primary Care Utilization and Colorectal Cancer Incidence and Mortality Among Medicare Beneficiaries: A Population-Based, Case-Contral Study. Ann Intern Med. 2013;159(7):437-446 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24081284 <Internet> http://annals.org/article.aspx?articleid=1742591
  40. Levin B, Lieberman DA, McFarland B et al Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology. 2008 May;134(5):1570-95 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18384785
  41. Lieberman D. Progress and challenges in colorectal cancer screening and surveillance. Gastroenterology. 2010 Jun;138(6):2115-26 PMID: https://www.ncbi.nlm.nih.gov/pubmed/20167216
  42. Whitlock EP, Lin JS, Liles E, Beil TL, Fu R. Screening for colorectal cancer: a targeted, updated systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2008 Nov 4;149(9):638-58 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18838718
  43. Center for Disease Control and Prevention (CDC) Vital Signs: Colorectal Cancer Screening Test Use - United States, 2012. MMWR. Nov 5, 2013 / 62(Early Release);1-8 http://www.cdc.gov/mmwr/preview/mmwrhtml/mm62e1105a1.htm
  44. Prescriber's Letter 21(3): 2014 Strategies for Improving Colon Cancer Screening. Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=300321&pb=PRL (subscription needed) http://www.prescribersletter.com
  45. 45.0 45.1 Mueller PS NEJM Journal Watch. March 14, 2014 Massachusetts Medical Society http://www.jwatch.org
    Saini SD et al. Role of quality measurement in inappropriate use of screening for colorectal cancer: Retrospective cohort study. BMJ 2014 Feb 26; 348:g1247 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24574474 <Internet> http://www.bmj.com/content/348/bmj.g1247
  46. 46.0 46.1 Young K Physician's First Watch, March 27, 2014 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
  47. Walter LC, Lindquist K, Nugent S et al Impact of age and comorbidity on colorectal cancer screening among older veterans. Ann Intern Med. 2009 Apr 7;150(7):465-73. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19349631
  48. 48.0 48.1 Brenner H et al Effect of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised controlled trials and observational studies. BMJ 2014;348:g2467 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24922745 <Internet> http://www.bmj.com/content/348/bmj.g2467
  49. Gross CP, McAvay GJ, Krumholz HM et al The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening. Ann Intern Med. 2006 Nov 7;145(9):646-53. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17088577
  50. 50.0 50.1 van Hees F et al Should Colorectal Cancer Screening Be Considered in Elderly Persons Without Previous Screening?: A Cost-Effectiveness Analysis. Ann Intern Med. 2014;160(11):750-759 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24887616 <Internet> http://annals.org/article.aspx?articleid=1877018
  51. 51.0 51.1 51.2 Holme O et al Effect of Flexible Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality. A Randomized Clinical Trial. JAMA. 2014;312(6):606-615 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25117129 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=1895247
    Brett AS et al Flexible Sigmoidoscopy for Colorectal Cancer Screening. More Evidence, Persistent Ironies. JAMA. 2014;312(6):601-602 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25117127 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=1895231
  52. 52.0 52.1 Weinberg DS et al Genetic and Environmental Risk Assessment and Colorectal Cancer Screening in an Average-Risk Population: A Randomized Trial. Ann Intern Med. 2014;161(8):537-545 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25329201 <Internet> http://annals.org/article.aspx?articleid=1916819
  53. 53.0 53.1 Kruse GR et al. Overuse of colonoscopy for colorectal cancer screening and surveillance. J Gen Intern Med 2015 Mar; 30:277 PMID: https://www.ncbi.nlm.nih.gov/pubmed/25266407
  54. 54.0 54.1 54.2 54.3 54.4 Wilt TJ, Harris RP, Qaseem A for the High Value Care Task Force of the American College of Physicians. Screening for Cancer: Advice for High-Value Care From the American College of Physicians. Ann Intern Med. 2015;162(10):718-725. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25984847 <Internet> http://annals.org/article.aspx?articleid=2294149
    Harris RP, Wilt TJ, Qaseem A for the High Value Care Task Force of the American College of Physicians. A Value Framework for Cancer Screening: Advice for High-Value Care From the American College of Physicians. Ann Intern Med. 2015;162(10):712-717 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25984846 <Internet> http://annals.org/article.aspx?articleid=2293237
  55. Imperiale TF et al Derivation and Validation of a Scoring System to Stratify Risk for Advanced Colorectal Neoplasia in Asymptomatic Adults: A Cross-sectional Study. Ann Intern Med. Published online 11 August 2015 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26259154 <Internet> http://annals.org/article.aspx?articleid=2424878
    Doubeni CA et al Precision Screening for Colorectal Cancer: Promise and Challenges. Ann Intern Med. Published online 11 August 2015 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26258984 <Internet> http://annals.org/article.aspx?articleid=2424868
  56. 56.0 56.1 56.2 U.S. Preventive Services Task Force (USPSTF) Draft Recommendation Statement. October 2015 Colorectal Cancer: Screening http://www.uspreventiveservicestaskforce.org/Page/Document/draft-recommendation-statement38/colorectal-cancer-screening2
  57. U.S. Preventive Services Task Force (USPSTF) Screening for colorectal cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2008 Nov 4;149(9):627-37. Epub 2008 Oct 6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18838716
  58. Rex DK, Johnson DA, Anderson JC et al American College of Gastroenterology guidelines for colorectal cancer screening 2009 [corrected]. Am J Gastroenterol. 2009 Mar;104(3):739-50 PMID: https://www.ncbi.nlm.nih.gov/pubmed/19240699
  59. 59.0 59.1 59.2 59.3 59.4 59.5 Canadian Task Force on Preventive Health Care Recommendations on screening for colorectal cancer in primary care. CMAJ. February 22, 2016 (Early Publication) <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26903355 <Internet> http://www.cmaj.ca/content/early/2016/02/22/cmaj.151125.full.pdf
  60. Lieberman DA. Clinical practice. Screening for colorectal cancer. N Engl J Med. 2009 Sep 17;361(12):1179-87. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19759380
  61. Weinberg DS, Schoen RE. In the clinic. Screening for colorectal cancer. Ann Intern Med. 2014 May 6;160(9). Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24798544
  62. 62.0 62.1 62.2 62.3 62.4 US Preventive Services Task Force Screening for Colorectal Cancer. US Preventive Services Task Force Recommendation. JAMA. Published online June 15, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27304597 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=2529486
    Ransohoff DF, Sox HC Clinical Practice Guidelines for Colorectal Cancer Screening. New Recommendations and New Challenges. JAMA. Published online June 15, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27304798 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=2529488
    Knudsen AB, Zauber AG, Rutter CM et al Estimation of Benefits, Burden, and Harms of Colorectal Cancer Screening Strategies: Modeling Study for the US Preventive Services Task Force. JAMA. 2016 Jun 15.
    Lin JS, Piper MA, Perdue LA et al Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2016 Jun 15 PMID: https://www.ncbi.nlm.nih.gov/pubmed/27305422
    US Preventive Services Task Force Final Recommendation Statement. Colorectal Cancer: Screening http://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/colorectal-cancer-screening2
    US Preventive Services Task Force Colorectal Cancer: Screening. October 27, 2020 Draft Recommendation Statement. https://uspreventiveservicestaskforce.org/uspstf/draft-recommendation/colorectal-cancer-screening3 Draft Evidence Review https://uspreventiveservicestaskforce.org/uspstf/document/draft-evidence-review/colorectal-cancer-screening3
  63. 63.0 63.1 63.2 Garcia-Albeniz X, Hsu J, Bretthauer M, Hernan MA Effectiveness of Screening Colonoscopy to Prevent Colorectal Cancer Among Medicare Beneficiaries Aged 70 to 79 Years: A Prospective Observational Study. Ann Intern Med. Published online 27 September 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27669524 <Internet> http://annals.org/article.aspx?articleid=2556139
  64. 64.0 64.1 Ladabaum U, Patel A, Mannalithara A et al. Predicting advanced neoplasia at colonoscopy in a diverse population with the National Cancer Institute colorectal cancer risk-assessment tool. Cancer 2016 Sep 1; 122:2663. PMID: https://www.ncbi.nlm.nih.gov/pubmed/27219715
  65. Inadomi JM Screening for Colorectal Neoplasia. N Engl J Med 2017; 376:149-156. January 12, 2017. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28076720 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMcp1512286
  66. 66.0 66.1 Atkin W, Wooldrage K, Parkin DM et al. Long term effects of once-only flexible sigmoidoscopy screening after 17 years of follow-up: The UK Flexible Sigmoidoscopy Screening randomised controlled trial. Lancet 2017 Feb 21; PMID: https://www.ncbi.nlm.nih.gov/pubmed/28236467 Free Article
    Pinsky PF. Flexible sigmoidoscopy screening: Is once enough? Lancet 2017 Feb 21; PMID: https://www.ncbi.nlm.nih.gov/pubmed/28236465 Free Article
  67. 67.0 67.1 67.2 Corley DA, Jensen CD, Quinn VP et al Association Between Time to Colonoscopy After a Positive Fecal Test Result and Risk of Colorectal Cancer and Cancer Stage at Diagnosis. JAMA. 2017;317(16):1631-1641 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28444278 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2620087
    Rutter CM, Inadom JM. Follow-up of Positive Fecal Test ResultsSooner Is Better, but How Much Better? JAMA. 2017;317(16):1627-1628. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28444260 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2620068
  68. 68.0 68.1 68.2 Lai JH, Park G, Gerson LB. Association between breast cancer and the risk of colorectal cancer: Systematic review and meta-analysis. Gastrointest Endosc. 2017 Apr 19. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28433614 <Internet> http://www.giejournal.org/article/S0016-5107(17)31810-2/pdf
  69. 69.0 69.1 69.2 69.3 69.4 69.5 Rex DK, Boland CR, Dominitz JA et al. Colorectal Cancer screening: Recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol 2017 Jun 6; PMID: https://www.ncbi.nlm.nih.gov/pubmed/28555630 https://www.nature.com/ajg/journal/vaop/ncurrent/full/ajg2017174a.html
  70. 70.0 70.1 Katsoula A, Paschos P, Haidich AB, Tsapas A, Giouleme O. Diagnostic accuracy of fecal immunochemical test in patients at increased risk for colorectal cancer: A meta-analysis. JAMA Intern Med 2017 Jun 19; <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28628706 <Internet> http://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2631561
    Leontiadis GI. Fecal immunochemical tests in patients at increased risk for colorectal cancer - is it prime time yet? JAMA Intern Med 2017 Jun 19 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28628694 <Internet> http://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2631557
  71. Swartz AW, Eberth JM, Josey MJ, Strayer SM Re-analysis of All-Cause Mortality in the U.S. Preventive Services Task Force 2016 Evidence Report on Colorectal Cancer Screening. Ann Intern Med. Aug 22, 2017. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28828493 <Internet> http://annals.org/aim/article/2650649/re-analysis-all-cause-mortality-u-s-preventive-services-task
  72. 72.0 72.1 Singal AG, Gupta S, Skinner CS et al Effect of Colonoscopy Outreach vs Fecal Immunochemical Test Outreach on Colorectal Cancer Screening Completion: A Randomized Clinical Trial. JAMA. 2017 Sep 5;318(9):806-815. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28873161 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2652650
    Rat C, Pogu C, Le Donne D et al Effect of Physician Notification Regarding Nonadherence to Colorectal Cancer Screening on Patient Participation in Fecal Immunochemical Test Cancer Screening: A Randomized Clinical Trial. JAMA. 2017 Sep 5;318(9):816-824. doi:http://dx.doi.org/ 10.1001/jama.2017.11387. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28873160 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2652649
    Pignone M, Miller DP Jr. Using Outreach to Improve Colorectal Cancer Screening. JAMA. 2017 Sep 5;318(9):799-800. No abstract available. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28873142 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2652630
  73. 73.0 73.1 Coronado GD, Rivelli JS, Fuoco MJ et al Effect of Reminding Patients to Complete Fecal Immunochemical Testing: A Comparative Effectiveness Study of Automated and Live Approaches. J Gen Intern Med. 2017 Oct 10 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29019046 https://link.springer.com/article/10.1007/s11606-017-4184
  74. 74.0 74.1 Selby K, Baumgartner C, Levin TR et al. Interventions to improve follow-up of positive results on fecal blood tests: A systematic review. Ann Intern Med 2017 Oct 17; 167:56. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29049756 <Internet> http://annals.org/aim/article/2657163/interventions-improve-follow-up-positive-results-fecal-blood-tests-systematichttp://annals.org/aim/article/2657163/interventions-improve-follow-up-positive-results-fecal-blood-tests-systematic
  75. 75.0 75.1 75.2 Jeon J, Du M, Schoen RE et al. Determining risk of colorectal cancer and starting age of screening based on lifestyle, environmental, and genetic factors. Gastroenterology 2018 Feb 16 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29458155 https://linkinghub.elsevier.com/retrieve/pii/S0016508518302245
  76. 76.0 76.1 76.2 Lauby-Secretan B, Vilahur N, Bianchini F, et al The IARC Perspective on Colorectal Cancer Screening. N Engl J Med. March 26, 2018 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29580179 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMsr1714643
  77. Kahi CJ, Pohl H, Myers LJ et al. Colonoscopy and colorectal cancer mortality in the Veterans Affairs health care system: A case-control study. Ann Intern Med 2018 Mar 13; <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29532085 <Internet> http://annals.org/aim/article-abstract/2674677/colonoscopy-colorectal-cancer-mortality-veterans-affairs-health-care-system-case
    Miller DP Jr., Denizard-Thompson N, Weaver KE et al. Effect of a digital health intervention on receipt of colorectal cancer screening in vulnerable patients: A randomized controlled trial. Ann Intern Med 2018 Mar 13 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29532054 <Internet> http://annals.org/aim/article-abstract/2674679/effect-digital-health-intervention-receipt-colorectal-cancer-screening-vulnerable-patients
  78. 78.0 78.1 Holme O et al. Effectiveness of flexible sigmoidoscopy screening in men and women and different age groups: Pooled analysis of randomised trials. BMJ 2017;356:i6673 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28087510 Free PMC Article <Internet> http://www.bmj.com/content/356/bmj.i6673
    Haug U. Flexible sigmoidoscopy screening for colorectal cancer. Different outcomes in men and women are a challenge for decision makers. BMJ 2017;356:j75 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28087640 <Internet> http://www.bmj.com/content/356/bmj.j75
    Holme O, Loberg M, Kalager M et al Long-Term Effectiveness of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality in Women and Men: A Randomized Trial. Ann Intern Med. 2018. April 24. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29710125 <Internet> http://annals.org/aim/article-abstract/2679355/long-term-effectiveness-sigmoidoscopy-screening-colorectal-cancer-incidence-mortality-women
  79. 79.0 79.1 79.2 79.3 79.4 Nelson R Begin Colorectal Cancer Screening at Age 45, Says ACS. Medscape - May 30, 2018. https://www.medscape.com/viewarticle/897351
    Wolf AMD, Fontham ETH, Church TR et al Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA: A Cancer Journal for Clinicians. May 30, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29846947 Free full text https://onlinelibrary.wiley.com/doi/full/10.3322/caac.21457
  80. 80.0 80.1 Wieten E, Schreuders EH, Grobbee EJ et al. Incidence of faecal occult blood test interval cancers in population-based colorectal cancer screening: A systematic review and meta-analysis. Gut 2018 Jun 22 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29934436 https://gut.bmj.com/content/early/2018/06/22/gutjnl-2017-315340
  81. Dougherty MK, Brenner AT, Crockett SD et al. Evaluation of interventions intended to increase colorectal cancer screening rates in the United States: A systematic review and meta-analysis. JAMA Intern Med 2018 Oct 15; PMID: https://www.ncbi.nlm.nih.gov/pubmed/30326005 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2706176
    Green BB. Colorectal cancer control: Where have we been and where should we go next? JAMA Intern Med 2018 Oct 15 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30326022 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2706173
  82. 82.0 82.1 82.2 82.3 82.4 82.5 Leddin D, Lieberman DA, Tse F et al. Clinical practice guideline on screening for colorectal cancer in individuals with a family history of nonhereditary colorectal cancer or adenoma: The Canadian Association of Gastroenterology Banff consensus. Gastroenterology 2018 Nov; 155:1325. PMID: https://www.ncbi.nlm.nih.gov/pubmed/30121253 https://www.gastrojournal.org/article/S0016-5085(18)34882-0/fulltext
  83. 83.0 83.1 Piper MS, Maratt JK, Zikmund-Fisher BJ et al. Patient attitudes toward individualized recommendations to stop low-value colorectal cancer screening. JAMA Netw Open 2018 Dec 7; 1:e185461. Not indexed in PubMed https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2717557
  84. 84.0 84.1 Tian Y, Kharazmi E, Sundquist K, Sundquist J, Brenner H, Fallah M. Familial colorectal cancer risk in half siblings and siblings: Nationwide cohort study. BMJ 2019;364:l803 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30872356 Free PMC Article https://www.bmj.com/content/364/bmj.l803
  85. Gupta N, Kupfer SS, Davis AM Colorectal Cancer Screening. JAMA. Published online April 25, 2019. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31021387 https://jamanetwork.com/journals/jama/fullarticle/2732299
  86. 86.0 86.1 Ladabaum U, Mannalithara A, Meester RGS, Gupta S, Schoen RE. Cost-effectiveness and national effects of initiating colorectal cancer screening for average-risk persons at age 45 years instead of 50 years. Gastroenterology 2019 Mar 28 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30930021 https://www.gastrojournal.org/article/S0016-5085(19)33578-4/pdf
  87. 87.0 87.1 87.2 Grobbee EJ, van der Vlugt M, van Vuuren AJ et al. Diagnostic yield of one-time colonoscopy vs one-time flexible sigmoidoscopy vs multiple rounds of mailed fecal immunohistochemical tests in colorectal cancer screening. Clin Gastroenterol Hepatol 2019 Aug 13; PMID: https://www.ncbi.nlm.nih.gov/pubmed/31419575 https://www.cghjournal.org/article/S1542-3565(19)30890-0/pdf
  88. 88.0 88.1 88.2 Helsingen LM et al. Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: A clinical practice guideline. BMJ 2019 Oct 2; 367:l5515. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31578196 https://www.bmj.com/content/367/bmj.l5515
    Buskermolen M et al. Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: A microsimulation modelling study. BMJ 2019 Oct 2; 367:l5383. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31578177 Free Article https://www.bmj.com/content/367/bmj.l5383
    Autier P. Personalised and risk based cancer screening. BMJ 2019 Oct 2; 367:l5558. Not indexed in PubMed https://www.bmj.com/content/367/bmj.l5558
  89. 89.0 89.1 89.2 89.3 Qaseem A, Crandall CJ, Mustafa RA et al Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: A Guidance Statement From the American College of Physicians. Ann Intern Med. 2019;171(9):643-654. Nov 5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31683290 https://annals.org/aim/fullarticle/2754194/screening-colorectal-cancer-asymptomatic-average-risk-adults-guidance-statement-from
    Pignone M Reconciling Disparate Guidelines: The American College of Physicians Colorectal Cancer Screening Guidance Statement. Ann Intern Med. 2019;171(9):671-672. Nov 5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31683292 https://annals.org/aim/article-abstract/2754203/reconciling-disparate-guidelines-american-college-physicians-colorectal-cancer-screening-guidance
  90. 90.0 90.1 Heisser T, Peng L, Weigl K, Hoffmeister M, Brenner H. Outcomes at follow-up of negative colonoscopy in average risk population: Systematic review and meta-analysis. BMJ 2019 Nov 13; 367:l6109 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31722884 Free PMC Article
  91. 91.0 91.1 Longstreth GF, Anderson DS, Zisook DS, Shi JM, Lin JC. Low rate of cancer detection by colonoscopy in asymptomatic, average-risk subjects with negative results from fecal immunochemical tests. Clin Gastroenterol Hepatol 2020 Jan 30; PMID: https://www.ncbi.nlm.nih.gov/pubmed/32007541 https://www.cghjournal.org/article/S1542-3565(20)30108-7/pdf
  92. 92.0 92.1 Pilonis ND et al. Long-term colorectal cancer incidence and mortality after a single negative screening colonoscopy. Ann Intern Med 2020 May 26; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32449884 https://www.acpjournals.org/doi/10.7326/M19-2477
  93. 93.0 93.1 Chiu HM, Jen GH, Wang YW et al Long-term effectiveness of faecal immunochemical test screening for proximal and distal colorectal cancers. Gut. 2021 Jan 25 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33495268 Free article.
  94. 94.0 94.1 94.2 Shaukat A, Kahi CJ, Burke CA et al ACG Clinical Guidelines: Colorectal Cancer Screening 2021. Am J of Gastroenterol 2021 March 116(3):458-479 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33657038 https://journals.lww.com/ajg/Fulltext/2021/03000/ACG_Clinical_Guidelines__Colorectal_Cancer.14.aspx
  95. 95.0 95.1 95.2 95.3 95.4 95.5 US Preventive Services Task Force Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2021;325(19):1965-1977 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34003218 https://jamanetwork.com/journals/jama/fullarticle/2779985
    Knudsen AB, Rutter CM, Peterse EFP et al Colorectal Cancer Screening. An Updated Modeling Study for the US Preventive Services Task Force. JAMA. 2021;325(19):1998-2011 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34003219 https://jamanetwork.com/journals/jama/fullarticle/2779986
    Lin JS, Perdue LA, Henrikson NB et al Screening for Colorectal Cancer. Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2021;325(19):1978-1997 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34003220 https://jamanetwork.com/journals/jama/fullarticle/2779987
    Ng K, May FP, Schrag D US Preventive Services Task Force Recommendations for Colorectal Cancer Screening - Forty-Five Is the New Fifty. JAMA. 2021;325(19):1943-1945 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34003238 https://jamanetwork.com/journals/jama/fullarticle/2780009
    Stewart DB Updated USPSTF Guidelines for Colorectal Cancer Screening. The Earlier the Better. JAMA Surg. Published online May 18, 2021 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34003208 https://jamanetwork.com/journals/jamasurgery/fullarticle/2780038
    Mehta SJ, Morris AM, Kupfer SS Colorectal Cancer Screening Starting at Age 45 Years - Ensuring Benefits Are Realized by All. JAMA Netw Open. 2021;4(5):e2112593 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34003278 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2779943
  96. 96.0 96.1 96.2 Ma W, Wang K, Nguyen LH et al Association of Screening Lower Endoscopy With Colorectal Cancer Incidence and Mortality in Adults Older Than 75 Years. JAMA Oncol. 2021;7(7):985-992. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34014275 PMCID: PMC8138747 (available on 2022-05-20) https://jamanetwork.com/journals/jamaoncology/fullarticle/2780056
    Bhoo-Pathy M, Bujang NNA, Ng CW Continuation of Screening Endoscopy for Colorectal Cancer in Older Adults. JAMA Oncol. 2021;7(7):973-975 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34014277 https://jamanetwork.com/journals/jamaoncology/fullarticle/2780062
  97. 97.0 97.1 97.2 97.3 Wang K, Ma W, Wu K et al. Long-term colorectal cancer incidence and mortality after colonoscopy screening according to individuals' risk profiles. J Natl Cancer Inst 2021 Sep 4; 113:1177. PMID: https://www.ncbi.nlm.nih.gov/pubmed/33734405 PMCID: PMC8418388 (available on 2022-03-18) https://academic.oup.com/jnci/article/113/9/1177/6178004
  98. 98.0 98.1 Fendrick AM, Princic N, Miller-Wilson LA et al Out-of-Pocket Costs for Colonoscopy After Noninvasive Colorectal Cancer Screening Among US Adults With Commercial and Medicare Insurance. JAMA Netw Open. 2021;4(12):e2136798. Dec 2. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34854909 Free article https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2786794
  99. 99.0 99.1 99.2 Bassett M If You Invite 455 People to Colonoscopy, You'll Stop One Case of Cancer. Risk of colorectal cancer reduced with screening in randomized trial, but less than expected. MedPage Today October 9, 2022 https://www.medpagetoday.com/hematologyoncology/coloncancer/101123 Bretthauer M, Loberg M, Wieszczy P et al Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death. N Engl J Med. 2022. Oct 9 PMID: https://www.ncbi.nlm.nih.gov/pubmed/36214590 https://www.nejm.org/doi/full/10.1056/NEJMoa2208375
  100. 100.0 100.1 Slomski A Colonoscopy Did Not Reduce Cancer Deaths in Trial. JAMA. 2022;328(20):2003-2004. November 22/29 PMID: https://www.ncbi.nlm.nih.gov/pubmed/36413232 https://jamanetwork.com/journals/jama/fullarticle/2798744
  101. Carethers JM JAMA Diagnostic Test Interpretation Stool-Based Screening Tests for Colorectal Cancer JAMA. Published online February 17, 2023 PMID: https://www.ncbi.nlm.nih.gov/pubmed/36800187 https://jamanetwork.com/journals/jama/fullarticle/2801813
  102. 102.0 102.1 102.2 102.3 El Halabi J et al. Frequency of use and outcomes of colonoscopy in individuals older than 75 years. JAMA Intern Med 2023 Apr 3; [e-pub] PMID: https://www.ncbi.nlm.nih.gov/pubmed/37010845 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2803491
  103. ACP Internist Weekly | Colorectal cancer | August 1, 2023 Start screening for colorectal cancer at age 50 years, ACP suggests. https://acpinternist.org/weekly/archives/2023/08/01/1.htm
    Qaseem A et al Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: A Guidance Statement From the American College of Physicians (Version 2). Ann Intern Med, 2023. Aug 1. PMID: https://www.ncbi.nlm.nih.gov/pubmed/37523709 https://www.acpjournals.org/doi/10.7326/M23-0779
    Bretthauer M, Yang YX. New American College of Physicians guidance on colorectal cancer screening: Less is more. Ann Intern Med 2023 Aug 1; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/37523706 https://www.acpjournals.org/doi/10.7326/M23-1695
  104. 104.0 104.1 104.2 Chung DC et al. A cell-free DNA blood-based test for colorectal cancer screening. N Engl J Med 2024 Mar 14; 390:973 PMID: https://www.ncbi.nlm.nih.gov/pubmed/38477985 https://www.nejm.org/doi/10.1056/NEJMoa2304714
    Reuters Health Information, July 29, 2024 US FDA Approves Guardant Health's Blood-based Cancer Test. https://www.medscape.com/s/viewarticle/us-fda-approves-guardant-healths-blood-based-cancer-test-2024a1000duo
  105. 105.0 105.1 Brooks, M FDA OKs First Multitarget Stool RNA Test for CRC Screening. Medscape. May 07, 2024 https://www.medscape.com/viewarticle/fda-oks-first-multitarget-stool-rna-test-crc-screening-2024a10008tu
  106. 106.0 106.1 Brooks M FDA OKs Next-Gen Cologuard Test for CRC Screening. Medscape. October 04, 2024 https://www.medscape.com/viewarticle/fda-oks-next-gen-cologuard-test-crc-screening-2024a1000i86
  107. 107.0 107.1 Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022
  108. QCancer https://qcancer.org/15yr/colorectal/

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