risk factors for cancer
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Etiology
risk factors
- noncancer health markers & disease are associated with excess risk for new cancer & cancer-related death[2]
- serum cholesterol < 240 mg/dL, inverse relationship > 240 mg/dL
- heart rate > 90/min
- diabetes mellitus & prediabetes
- proteinuria
- GFR < 60 or > 90 mL/min/1.73 m2
- uric acid < 300 umol/L
- physical activity mitigates these risks
- adverse life style[2]
- nonideal body-mass index
- alcohol consumption
- insufficient fruit & vegetable intake
- insufficient physical activity
- smoking
Management
- see prevention of cancer
- moderate to vigorous physical activity associated with
- relative reduction in risk for 13 cancers
- 42% lower risk for esophageal adenocarcinoma
- 23% lower for renal carcinoma
- 20% lower for myeloid leukemia
- relative increase in risk for 2 cancers
- 27% higher risk for malignant melanoma
- 65% higher risk for prostate cancer
- relative reduction in risk for 13 cancers
More general terms
More specific terms
- risk factors for breast cancer & management of high-risk women
- risk factors for colon cancer in patients with ulcerative colitis
Additional terms
References
- ↑ Moore SC et al. Association of leisure-time physical activity with risk of 26 types of cancer in 1.44 million adults. JAMA Intern Med 2016 May 16; PMID: https://www.ncbi.nlm.nih.gov/pubmed/27183032
- ↑ 2.0 2.1 2.2 Tu H, Wen CP, Tsai SP, et al. Cancer risk associated with chronic diseases and disease markers: Prospective cohort study. BMJ 2018 Jan 31; 360:k134 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29386192 Free PMC Article <Internet> http://www.bmj.com/content/360/bmj.k134