ketorolac (Toradol, Acular, Acuvail)

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Introduction

Tradenames: Toradol, Acular. ketorolac tromethamine.

Indications

Contraindications

pregnancy category = c

pregnancy category = d

safety in lactation = -

safety in lactation = ?

Dosage

Tabs: 10 mg.

Injection: 15 mg, 30 mg, 60 mg (single-dose syringes).

Ophthalmic: (Acular) 1 drop QID (0.5%)

Pharmacokinetics

elimination via liver

elimination via kidney

1/2life = 4-10 hours

protein binding = >99 %

elimination by hemodialysis = -

elimination by peritoneal dialysis = -

Monitor

Adverse effects

Drug interactions

Laboratory

Mechanism of action

More general terms

Component of

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. 2.0 2.1 Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Clinical Guide to Laboratory Tests, NW Tietz (ed) 3rd ed, WB Saunders, Philadelpha 1995
  5. 5.0 5.1 Prescriber's Letter 17(7): 2010 Recommended Lab Monitoring for Common Medications Liver Function Test Scheduling Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=260704&pb=PRL (subscription needed) http://www.prescribersletter.com
  6. Prescriber's Letter 19(6): 2012 COMMENTARY: Common Questions About Ketorolac GUIDELINES: Guidelines for Prevention of NSAID-Related Ulcer Complications (2009) Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=280607&pb=PRL (subscription needed) http://www.prescribersletter.com
  7. 7.0 7.1 Deprecated Reference

Database