depolarization

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Introduction

A process of excitable cells whereby a polarized cell or fiber loses its potential difference (charge) across a semipermeable membrane. Depolarization of neurons may be associated with an action potential. The depolarization is generally due to opening of Na+ channels with influx of Na+ ions. Ca+2 channels may also be associated with depolarization.

More general terms

References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999