chlordiazepoxide (Librium)

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Introduction

Tradename: Librium. DEA-controlled substance: class 4.

Indications

Contraindications

Caution:

pregnancy category = d

safety in lactation = -

Dosage

Tabs: 5, 10, 25 mg.

Powder for injection: 100 mg

Dosage adjustment in renal failure

Pharmacokinetics

elimination via liver

1/2life = 6-30 hours

protein binding = 95 %

elimination by hemodialysis = -

Adverse effects

Drug interactions

Laboratory

Mechanism of action

More general terms

Component of

References

  1. 1.0 1.1 The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996.
  2. 2.0 2.1 Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 7
  3. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  4. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  5. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  6. 6.0 6.1 6.2 Medical Knowledge Self Assessment Program (MKSAP) 19. American College of Physicians, Philadelphia 2021

Database