Figure: CXC ligand & receptor binding

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A58435.png

Introduction

CXCR1 <- CDw128, interleukin 8 receptor alpha

CXCR2 <- interleukin 8 receptor beta

CXCR3 <- CD182, G protein coupled receptor 9

CXCR4 <- CD184, fusin, LESTR, NPRVL, SDF-1 receptor

CXCR5 <- Burkitt's lymphoma receptor 1

CXCR6 <- G protein coupled receptor STRL33, BONZO



CXCL1 -> gro-alpha, neutrophil activating protein 3, MGSA

CXCL2 -> gro-beta, MIP-2 alpha

CXCL3 -> gro-gamma, MIP-2 beta

CXCL4 -> platelet factor 4

CXCL5 -> ena78

CXCL6 -> granulocyte chemotactic protein 2 (GCP-2)

CXCL7 -> beta-thromboglobulin 2

CXCL8 -> interleukin 8

CXCL9 -> IFN gamma induced monokine, MIG

CXCL10 -> IP-10

CXCL11 -> IP-9, I-TAC

CXCL12 -> stromal cell derived factor 1 (SDF1), pre-B growth stimulating factor (PBSF)

CXCL13 -> B cell attracting chemokine 1

CXCL16 -> SR-PSOX

References

  1. Tran PB, Miller RJ. Chemokine receptors: signposts to brain development and disease. Nat Rev Neurosci. 2003 Jun;4(6):444-55. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12778117 Review.