C-X-C motif chemokine 5; ENA-78(1-78); epithelial-derived neutrophil-activating protein 78; neutrophil-activating peptide ENA-78; small-inducible cytokine B5 (CXCL5 ENA78 SCYB5)

Function

• role in neutrophil activation
• in vitro, ENA-78(8-78) & ENA-78(9-78) show a threefold higher chemotactic activity for neutrophils
• N-terminal processed forms ENA-78(8-78) & ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes

Structure

• belongs to the intercrine alpha (chemokine CxC) family

Compartment

secreted

More general terms

• CXC chemokine; alpha chemokine

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6374
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6374
• OMIM: https://mirror.omim.org/entry/600324
• UniProt: http://www.uniprot.org/uniprot/P42830.html