Structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6, chromosome-associated polypeptide, hCAP, bamacan, basement membrane-associated chondroitin proteoglycan, CSPG6, BAM, BMH, SMC3, SMC3L1)

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Function

Structure

  • the flexible hinge domain, which separates the large intramolecular coiled coil regions, allows the heterotypic interaction with the corresponding domain of SMC1A or SMC1B, forming a V-shaped heterodimer
  • the two heads of the heterodimer are then connected by different ends of the cleavable RAD21 protein, forming a ring structure (putative)
  • belongs to the SMC family, SMC3 subfamily

Compartment

Pathology

Notes

More general terms

Component of

References

Database