synaptonemal complex protein 2 (SCP-2, synaptonemal complex lateral element protein, hsSCP2, SYCP2, SCP2)

Function

• component of axial/lateral elements of synaptonemal complexes during meiotic prophase
• role in organization of chromatin by temporarily binding to DNA scaffold attachment regions
• requires SYCP3, but not SYCP1, to be incorporated into axial/lateral elements
• heterodimer with SYCP3
• interacts with SYCP3, SMC1L1 & SMC3

Compartment

• nucleus
• in axial/lateral elements of tripartite segments of synaptonemal complexes

More general terms

• nuclear protein

Component of

• synaptonemal complex

Database

• OMIM: https://mirror.omim.org/entry/604105
• UniProt: http://www.uniprot.org/uniprot/Q9BX26.html