kinesin family member 3B (Kif3b, microtubule plus end-directed kinesin motor 3B, HH0048)

Function

• role in tethering the chromosomes to the spindle pole & in chromosome movement
• microtubule-based anterograde translocator for membranous organelles
• plus end-directed microtubule sliding activity in vitro (putative)
• heterodimer of KIF3A & KIF3B
• interacts directly with IFT20 (putative)
• interacts with the SMC3 subunit of the cohesin complex

Structure

• belongs to the kinesin-like protein family, kinesin 2 subfamily
• contains 1 kinesin-motor domain

More general terms

• kinesin family 3 (Kif3)

Database

• OMIM: https://mirror.omim.org/entry/603754
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9371
• UniProt: http://www.uniprot.org/uniprot/O15066.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9371