C-Jun-amino-terminal kinase-interacting protein 1; JIP-1; JNK-interacting protein 1; islet-brain 1; IB-1; JNK MAP kinase scaffold protein 1; mitogen-activated protein kinase 8-interacting protein 1 (MAPK8IP1, IB1, JIP,1 PRKM8IP)

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Function

Structure

Compartment

Expression

Pathology

Notes

  • a chemically synthesized cell-permeable peptide of the minimal inhibitory domain decreases brain lesions in both transient & permanent ischemia
  • the level of protection is still high when administered 6-12 hours after ischemia

More general terms

Additional terms

References

  1. Waeber G et al The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes. Nature Genetics 24:291-5, 2000 PMID: https://www.ncbi.nlm.nih.gov/pubmed/10700186
  2. UniProt http://www.uniprot.org/uniprot/Q9UQF2.html

Database