RNA splicing

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Introduction

Splicing or excision of introns from RNA transcribed from the DNA coding region of a gene during the formation of mRNA. About 60% of genes encoding proteins are expressed in different isoforms via alternative splicing of different exons from the initial gene transcript.

More general terms

Additional terms

References

  1. Alperts et al Molecular Biology of the Cell, Garland Publishing, New York, NY 1989
  2. Kornblihtt AR. Promoter usage and alternative splicing. Curr Opin Cell Biol. 2005 Jun;17(3):262-8. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15901495