predisposing factors associated with delirium

Introduction

From reference:

• older age
• cognitive impairment, dementia
• functional impairment:
  • physical impairment, visual impairment, hearing impairment, frailty
• cardiovascular disease
• multiple comorbidities
• CNS disease: stroke, Parkinson's disease, previous delirium, olfactory disorder
• alcohol use
• male
• depression
• lower level of education
• malnutrition
• diabetes mellitus
• tobacco use
• anemia
• psychiatric disorder or trait
• female (does not make any sense; how can both male & female be predisposing?)
• multiple medications
• psychoactive medication
• malignant neoplasm
• chronic pain
• pulmonary disease: obstructive sleep apnea, COPD
• poor sleep quality
• chronic kidney disease
• non-English language
• narcotic analgesic
• white race
• vitamin D deficiency
• anticholinergic agents
• biomarkers
  • biomarkers of neurodegeneration:
    • amyloid-beta 42 in CSF
    • MRI white matter hyperintensities
    • reduction in gray matter
    • thinner cerebral cortex
  • SNPs (SNVs) in DRD2 & SLC6A3
  • APOE4
  • AG haplotype of GRIN3A
  • COMT Val-127

More general terms

• risk factors for delirium

Additional terms

• delirium (acute confusional state)