MLL complex

Function

• histone methylation, possibly other chromosomal functions

Structure

• subunits:
  • MLL, ASH2L, RBBP5, DPY30, WDR5, MEN1, HCFC1 & HCFC2
• facultative components include:
  • C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 & TEX10

More general terms

• molecular complex