host cell factor 2 (HCF-2, C2 factor, HCFC2)

Function

• binds MLL
• detected in a histone methyltransferase complex containing MLL, ASH2L, WDR5, RBBP5 & MEN1

Structure

• contains 3 fibronectin F3 modules
• contains 4 Kelch repeats

Compartment

cytoplasm, nucleus

Expression

• highly expressed in testis
• detected at lower levels in spleen, thymus, prostate, ovary, small intestine, colon

More general terms

• protein subunit

Database

• OMIM: https://mirror.omim.org/entry/607926
• UniProt: http://www.uniprot.org/uniprot/Q9Y5Z7.html