transcription initiation factor TFIID subunit 6; p70TFIID; RNA polymerase II TBP-associated factor subunit E; transcription initiation factor TFIID 70 kD subunit; TAF(II)70; TAFII-70; TAFII70; transcription initiation factor TFIID 80 kD subunit; TAF(II)80; TAFII-80; TAFII80 (TAF6, TAF2E, TAFII70)

Function

• component of TFIID complex, PCAF complex & TFTC complex
• the TAF6-TAF9 heterodimer forms an octamer complex with the TAF4B-TAF12 heterodimer
• interacts with the GTFs, GTF2E1 & GTF2F1

Structure

belongs to the TAF6 family

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

• transcription factor IID subunit
• phosphoprotein

Component of

• transcription factor IID (TFIID)
• PCAF complex; coactivator for p53/TP53-dependent transcriptional activation; PCAF histone acetylase complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6878
• OMIM: https://mirror.omim.org/entry/602955
• UniProt: http://www.uniprot.org/uniprot/P49848.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6878