transcription initiation factor TFIID subunit 12; transcription initiation factor TFIID 20/15 kD subunits; TAFII-20/TAFII-15; TAFII20/TAFII15 (TAF12, TAF15, TAF2J, TAFII20)

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Function

components of TFIID complex, PCAF histone acetylase complex, STAGA transcription coactivator-HAT complex & TBP-free TAFII complex (TFTC)
interacts directly with TBP
additional interactions between TAFII20 & TAFII28 or TAFII30

Structure

belongs to the TAF12 family
contains 1 histone-fold domain

Compartment

Alternative initiation

named isoforms=2

Expression

More general terms

Component of

References

↑ Chiang CM, Roeder RG. Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science. 1995 Jan 27;267(5197):531-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7824954
↑ UniProt http://www.uniprot.org/uniprot/Q16514.html
↑ NIEHS-SNPs http://egp.gs.washington.edu/data/taf12/

Database

Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6883
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6883
OMIM: https://mirror.omim.org/entry/600773
UniProt: http://www.uniprot.org/uniprot/Q16514.html

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