PCAF complex; coactivator for p53/TP53-dependent transcriptional activation; PCAF histone acetylase complex

Function

• acetylates histones within a nucleosome
• human analog of the yeast SAGA complex

Structure

• subunits:
  • TADA2L/ADA2, TADA3L/ADA3, TAF5L/PAF65beta, TAF6L/PAF65alpha, TAF10/TAFII30, TAF12/TAFII20, TAF9/TAFII31, TRRAP, SUPT3H

More general terms

• molecular complex
• histone acetyltransferase