transcription initiation protein SPT3 homolog (SPT3-like protein, SUPT3H, SPT3)

Function

• transcriptional activator (putative)
• component of the PCAF complex
• component of the TFTC-HAT complex
• associates with TAFII31 & GCN5L2

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

• expressed in all tissues tested, including pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart

More general terms

• protein subunit

Component of

• PCAF complex; coactivator for p53/TP53-dependent transcriptional activation; PCAF histone acetylase complex
• TFTC-HAT complex (TATA-binding protein-free TAF complex, TBP-free TAFII complex, TFTC)

Database

• OMIM: https://mirror.omim.org/entry/602947
• UniProt: http://www.uniprot.org/uniprot/O75486.html