transcription initiation factor TFIID subunit 11; TFIID subunit p30-beta; transcription initiation factor TFIID 28 kD subunit; TAF(II)28; TAFII-28; TAFII28 (TAF11, TAF2I, PRO2134, p28TFIID)

Function

• component of TFIID, both TFIID-alpha & TFIID-beta (see TFIID)
• interacts with TAF13 both in vitro & intracellularly
• also interacts directly with TBP
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• TBP & TAFII18 bind to distinct domains of TAFII28
• belongs to the TAF11 family

Compartment

nucleus

More general terms

• transcription factor IID subunit
• phosphoprotein

Component of

• transcription factor IID (TFIID)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6882
• OMIM: https://mirror.omim.org/entry/600772
• UniProt: http://www.uniprot.org/uniprot/Q15544.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6882