prostaglandin E2 (PGE2, dinoprostone, Prepidil, Cervidil)

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Pharmacology

dinoprostone Tradenames: Prepidil, Cervidil

Indications

Adverse effects

Mechanism of action

Comparative biology

* contrast effects of macrophage PGE2 in aging brain vs aging muscle

More general terms

Additional terms

References

  1. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  2. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
  3. 3.0 3.1 Chen C et al, J Neurophysiol 87:2851, 2002
  4. 4.0 4.1 Deprecated Reference
  5. 5.0 5.1 5.2 Minhas PS, Latif-Hernandez A, McReynolds MR et al. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature 2021 Feb; 590:122 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33473210 https://www.nature.com/articles/s41586-020-03160-0
  6. 6.0 6.1 6.2 Palla AR, Ravichandran M, Wang YX et al. Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. Science 2021 Jan 29; 371:eabc8059 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33303683 https://science.sciencemag.org/content/371/6528/eabc8059

Database