synaptic plasticity; neuronal plasticity

Introduction

The ability of a synapse to undergo remodeling in response to activity, including ionic currents & depolarization. Synaptic plasticity (via long-term potentiation {in part}) is thought to form the basis of learning & memory.

Similarities with synaptogensis.

In humans, MRI-detectable changes in grey matter volume can accompany acquisition of a skill. Cessation of practice of the skill can result in reduction in grey matter acquired with skill acquisition.

Proteins implicated in synaptic plasticity:

• also see long-term potentiation
• ARC

More general terms

• physiology
• plasticity

Additional terms

• long term depression (LTD)
• long term potentiation (LTP)
• paired-pulse facilitation
• synaptogenesis