prostaglandin E2 receptor EP2 subtype; prostanoid EP2 receptor; PGE receptor, EP2 subtype (PTGER2)

Function

• receptor for prostaglandin E2 (PGE2)
• activity is mediated by Gs proteins that stimulate adenylate cyclase
• increase in intracellular cAMP mediates relaxing effect of PTGER2 on smooth muscle

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

placenta & lung

More general terms

• prostaglandin-E [PGE] receptor
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5732
• OMIM: https://mirror.omim.org/entry/176804
• UniProt: http://www.uniprot.org/uniprot/P43116.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5732